Background/Aims: We report a study in patients with mucinous and nonmucinous appendiceal adenocarcinoma treated surgically whose records were examined to elucidate their clinicopathologic features and prognostic factors for survival. Methods: The medical records of 34 patients with mucinous and nonmucinous appendiceal adenocarcinoma (1991–2005) were retrospectively reviewed. Results: There was no significant difference between mucinous and nonmucinous tumors in patient demographics, clinicopathologic features, type of operation and outcome. Nonmucinous tumors had a higher incidence of leukocytosis than mucinous ones. The overall 5-year survival rate for 34 patients with appendiceal adenocarcinoma was 35.8%. In the univariate analysis, predictors of survival were the type of operation, resectability, carcinomatosis and tumor stage. Tumor stage significantly influenced patient survival in the multivariate analysis. Conclusion: Mucinous appendiceal adenocarcinoma had clinicopathologic characteristics and a prognosis similar to nonmucinous, except that there was more leukocytosis in nonmucinous tumors. Tumor stage is an independent predictor for survival among patients with appendiceal adenocarcinoma.

Keywords:
Adenocarcinoma, appendiceal, Pseudomyxoma peritonei, Survival predictors
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© 2008 S. Karger AG, Basel
2008
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