Background: The management of rectal carcinoma has changed significantly over the last decade. We studied the changing trends in the management of rectal carcinoma over a 7-year period in a district general hospital. Methods: A retrospective analysis of all patients with histologically proven rectal adenocarcinoma who underwent operative treatment between January 1991 and December 1997 was performed. The type of operative procedure, local recurrence rate and completeness of pathology reporting was documented. Results: There were 200 operative procedures: 102 anterior resections (AR), and 98 abdominoperineal resections (APR). This included 17 palliative resections because of metastatic disease (n = 8) or extensive local invasion (n = 7) or both (n = 2). The APR rate steadily declined from 72% in 1991 to 19% in 1997 (p < 0.005). Subspecialist ‘colorectal’ surgeons performed only 24% of the operations in 1991 but the figure for 1997 was 85% (p < 0.01). No circumferential resection margin was reported in 1991 but was reported in 85% of the cases in 1997 (p < 0.001). There was a steady increase in stapled anastomoses from 43% in 1991 to 93% in 1997 (p < 0.03). There were 15 local recurrences following ‘curative’ resection; 7 following APR and 8 following AR (n.s.). Conclusion: There was a significant increase in the rate of restorative resection of rectal cancer with a concomitant reduction in permanent stoma formation; this may be attributed to an increase in subspecialisation. Despite this, a low rate of local recurrence was maintained throughout the study period.

1.
Royal College of Surgeons of England and Association of Colonproctology of Great Britain and Ireland: Guidelines for the management of colorectal cancer. 1996, June 9.
2.
Goligher JC: Incidence and Pathology of Carcinoma of the Colon and Rectum: Surgery of the Anus, Rectum and Colon, ed 4. London, Ballière Trindall, 1980, pp 375–376.
3.
Benotti PN, Karbassi A, Ravikumar TS, et al: Management of regional and local tumour recurrence; in Steele G, Cady B (eds): General Surgical Oncology. Philadelphia, Saunders, 1992, pp 341–353.
4.
NHS Centre for Reviews and Dissemination, University of York: Effective Health Care: The management of colorectal cancer. Dec 1997, vol 3, no. 6.
5.
Mella J, Biffin A, Radcliffe AG, Stamatakis JD, Steele RJC: Population-based audit of colorectal cancer management in two UK health regions. Br J Surg 1997;84:1731–1736.
6.
Leff EI, Shaver JO, Hoexter B, et al: Anastomotic recurrences after low anterior resection. Stapled vs. handsewn. Dis Colon Rectum 1985;28:164–167.
7.
Amato A, Pescatori M, Butti A: Local recurrence following abdominoperineal excision and anterior resection for rectal carcinoma. Dis Colon Rectum 1991;34:317–322.
8.
Rosen CB, Beart RW Jr, Ilstrup DM: Local recurrence of rectal carcinoma after hand-sewn and stapled anastomoses. Dis Colon Rectum 1985;28:305–309.
9.
Sarker SK, Chaudhry R, Sinha VK: A comparison of stapled vs. hand-sewn anastomoses in anterior resection for carcinoma of the rectum. Indian J Cancer 1994;31:133–137.
10.
Terranova O, Celi D, Martella B, Battocchio F: Local recurrence of rectal cancer: Anterior resection versus abdomino-perineal resection: Int Surg 1988;73:111–113.
11.
Jatzko G, Lisborg P, Wette V: Improving survival rates for patients with colorectal cancer: Br J Surg 1992;79:588–591.
12.
Bozetti F, Mariani L, Meeli R, Doci R, Montalto F, Andreola S, Gennari L: Cancer of the middle and the lower rectum: Local and distant recurrence, and survival in 350 radically resected patients. J Surg Oncol 1996;62:207–213.
13.
Sagar PM, Pemberton JH: Surgical management of locally recurrent rectal cancer. Br J Surg 1996;83:293–304.
14.
Avradopoulos KA, Vezeridis MP, Wanebo HJ: Pelvic exenteration for recurrent rectal cancer. Adv Surg 1996;29:215–233.
15.
Keighley MRB, Williams NS: Surgery of the Anus, Rectum and Colon. London, Saunders, 1993, pp 1057–1063.
16.
Cummings BJ: A critical review of adjuvant preoperative radiation therapy for adenocarcinoma of the rectum. Br J Surg 1986;73:332–338.
17.
Pricolo VE, Potenti FM: Modern management of rectal cancer. Dig Surg 2001;18:1–20.
18.
Bruch JP, Shiedeck THK, Schwandner O: Laparoscopic colorectal surgery: A five-year experience. Dig Surg 1999;16:45–54.
19.
Heald RJ, Husband EM. Ryall RDH: The mesorectum in rectal cancer surgery – The clue to pelvic cancer surgery. Br J Surg 1982;69:613–616.
20.
MacFarlane JK, Ryall RDH, Heald RJ: Mesorectal excision for rectal cancer. Lancet 1993;341:457–459.
21.
Bull AD, Biffin AHB, Mella J, Radcliffe AG, Stamatakis JD, Steele RJ, Williams GT: Colorectal cancer pathology reporting: A regional audit. J Clin Pathol 1997;50:138–142.
22.
Morson BC, Vaughan EG, Bussey HJR: Pelvic recurrence after excision of rectum for carcinoma. Br Med J 1963;ii:13–18.
23.
Adolf M, Arnaud JP, Schloegel M, Thibaud D: Factors influencing local recurrence after abdominoperineal resection for cancer of the rectum. Dis Colon Rectum 1985;28:413–415.
Copyright / Drug Dosage / Disclaimer
Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher.
Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.
You do not currently have access to this content.