... of tetracycline in the field of dermatology and possible mechanisms of action. This comprehensive review encompasses all possible indications of tetracyclines besides acne vulgaris and rosacea: hidradenitis suppurativa, autoimmune bullous dermatoses, vitiligo, alopecia, prurigo pigmentosa, granulomatous...

...Hyun Jeong Ju; Jung Min Bae Background: Treatment of vitiligo seeks to achieve three goals: cessation of disease progression, regeneration of pigmentation, and prevention of recurrence. Summary: Number of nonsurgical interventions are available that suppress the autoimmune response and regenerate...

...Tithi Dutta; Sambuddha Sengupta; Suchismita Adhya; Arpan Saha; Debmalya Sengupta; Ritisri Mondal; Swarnadru Naskar; Samsiddhi Bhattacharjee; Mainak Sengupta Introduction: Vitiligo is a common depigmentation disorder characterized by defined white patches on the skin and affecting around 0.5% to 2...

...Atefeh Shahbazi; Manuchehr Abedi Valugerdi; Sepide Kazemi; Sarvenaz Samadi Kochaksaraei; Mohammad Hassan Naseh; Nasser Aghdami; Behnam Sadeghi Background: Vitiligo is a common depigmentation skin disease associated with significant psychosocial morbidity and profound effect on the quality of life...

...] age was 32.4 [14.3] years, mean follow-up was 30.4 [22.5] months, 63.8% were male; 55% were dark-skinned individuals [Fitzpatrick IV–VI]) were included. The mean percent change in the Vitiligo Area Scoring Index (VASI) was 80.2 (±23.7; RD of 7.3) in patients with focal/segmental vitiligo (SV), 58.3...

...Reema Patel; Amit G. Pandya; Vanja Sikirica; Kavita Gandhi; Shoshana R. Daniel; Kathryn P. Anastassopoulos; Yuji Yamaguchi; Lynne Napatalung; Rebecca Baik; Khaled Ezzedine Background: Vitiligo is an autoimmune disorder that causes patchy loss of skin pigmentation. Up to 2.16% of pediatric patients...

...Sheng-Hsiang Ma; Po-Chien Wu; Jin-Yu Chang; Yun-Ting Chang; Ying-Xiu Dai Background: Vitiligo is a skin depigmentation disorder that results from the autoimmune destruction of cutaneous melanocytes. Several ocular abnormalities, including uveitis, dry eye, glaucoma, and retinal diseases, have been...

...Brent J. Doolan; Michelle Weaich; Joanne Mamo; Monisha Gupta Autologous non-cultured epidermal cellular grafting is the treatment of choice for patients with stable refractory vitiligo. Recently, studies have shown cost-effective alternatives for this procedure, superseding previous techniques...

...María Luisa Peralta-Pedrero; Denisse Herrera-Bringas; Karla Samantha Torres-González; Martha Alejandra Morales-Sánchez; Fermín Jurado Santa-Cruz; Agles Cruz-Avelar Background: Vitiligo has an unpredictable course and a variable response to treatment. Furthermore, the improvement of some vitiligo...

... in vitiligo and has usually been clinically measured by the assessment of the minimal erythema dose (MED) after phototesting. Objectives: To assess the photoadaptive response in vitiligo and healthy skin after NB-UVB phototherapy not only clinically, but also by spectrophotometry. Materials and Methods...

...Juliana Catucci Boza; Natalia Giongo; Priscilla Machado; Roberta Horn; Amanda Fabbrin; Tania Cestari Background: Vitiligo can negatively affect a patient's quality of life (QoL). A specific questionnaire has been developed and validated in the English language: the vitiligo-specific quality-of-life...

...Harsimer Singh; Muthu Sendhil Kumaran; Anupama Bains; Davinder Parsad Background: Despite continued progress towards elucidation of the biochemical, genetic and immunopathological pathways in vitiligo, a definitive cure remains elusive. The initial therapy must be directed to arrest disease...

...Jennifer L. Herrmann; Erica Syklawer; Madeline Tarrillion; Madeleine Duvic; Lauren C. Hughey Background: Few reports have described vitiligo developing in patients with cutaneous T-cell lymphoma (CTCL). Objective: We sought to identify possible factors that might predispose patients with CTCL...

...Nicole Gunasekera; George F. Murphy; Vaneeta M. Sheth Inflammatory vitiligo with raised borders (IVRB) is a rare subtype of vitiligo described as having a rim of raised erythema at the periphery of the depigmented patches. The etiology is poorly understood, and there are few reports of successful...

...: It is believed that vitiligo has an impact on the overall patient quality of life (QoL). Objective: To estimate QoL in a fairly large sample of Italian vitiligo patients by using the Dermatology Life Quality Index (DLQI) questionnaire. Methods: One hundred and sixty-one vitiligo patients referred to 9...

... autoantibodies have been observed in vitiligo patients, but differences in rate are present according to countries in which the studies were performed, perhaps owing to ethnic diversities or different trigger factors. Objective: To estimate the prevalence of circulating autoantibodies and overt autoimmune...

...Vaneeta M. Sheth; Ye Guo; Abrar A. Qureshi Background: Vitiligo is a common disorder of depigmentation that has been associated with other autoimmune diseases. No recent large-scale data exist on the rates of comorbidities associated with vitiligo from the United States population. Objectives...

...Aslı Şenol; Ayşe Deniz Yücelten; Pınar Ay Background: No vitiligo-specific quality of life scale exists. Objective: To develop a reliable and valid quality of life scale for vitiligo patients. Methods: The content was derived from in-depth interviews with vitiligo patients. The internal consistency...

...İkbal Esen Aydıngöz; İlknur Bingül; Semra Doğru-Abbasoğlu; Pervin Vural; Müjdat Uysal Background: Vitiligo is a progressive depigmenting disorder characterized by the loss of functional melanocytes from the epidermis. The etiopathogenesis of vitiligo is still unclear. Vitamin D has both stimulatory...

...Ene Reimann; Külli Kingo; Maire Karelson; Paula Reemann; Ulvi Loite; Maris Keermann; Kristi Abram; Eero Vasar; Helgi Silm; Sulev Kõks Background: Dopamine has been proven to be toxic for melanocytes. In vitiligo patients the level of dopamine is increased and the functioning of several enzymes...