... of scleromyxedema with multiple myeloma (8.7%) and macroglobulinemia Waldenström (3.5%). A man with scleromyxedema, IgG lambda paraproteinemia, and sclerodactylia – as a special sign of scleromyxedema – is reported. Melphalan is the drug of choice in serious cases, but not effective in sclerodactylia...

.... Sclerodactylia was present and represented a yet undescribed manifestation of the disease. 7 10 2009 © 1996 S. Karger AG, Basel 1996 Copyright / Drug Dosage / Disclaimer Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized...

..., progressive nail dystrophy, sclerodactylia and spontaneous uleerations. These features were seen on the digits with sensory supply from the median nerve. The patient had hand paresthesias for at least 10 years. No abnormal results were found in biochemical, hematological or immunological determinations...