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Keywords: Retinoic acid
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Journal: Dermatology
Dermatologica (1977) 154 (6): 330–337.
Published Online: 15 October 2009
...J.E. Birnbaum Application of retinoic acid (vitamin A acid) to animal and human skin has been reported to produce cutaneous, proliferative lesions which microscopically and histochemically resemble those of psoriasis. In the present studies, the daily application of a 0.1 % solution of retinoic...
Journal Articles
Journal Articles
Journal: Dermatology
Dermatologica (1977) 155 (4): 200–205.
Published Online: 14 October 2009
.... Verrucous nevus Epidermal nevus Retinoic acid Retinoid Dermatológica 155: 200-205 (1977) Systemic Retinoid Therapy of Systematized Verrucous Epidermal Nevus (With I colour plate) R. Happle, W. Kastrup and E. Macher Department of Dermatology, University of Münster, Münster Key Words. Verrucous nevus...
Journal Articles
Journal: Dermatology
Dermatologica (1986) 173 (4): 163–173.
Published Online: 13 October 2009
...Georges Siegenthaler; Jean-Hilaire Saurat; Denis Salomon; Yves Mérot We have previously found an important increase of cellular retinoic acid-binding protein (CRABP) in psoriatic plaques whereas the cellular retinol-binding protein (CRBP) was not elevated compared to normal human skin...
Journal Articles
Journal Articles
Journal: Dermatology
Dermatologica (1987) 175 (Suppl. 1): 8–12.
Published Online: 09 October 2009
...F. Chytil; D.R. Sherman The main physiological function of natural retinoids, i.e. the dietary micronutrient retinol and its metabolite retinoic acid, is in proper differentiation and maintenance of differentiated state of many if not all epithelia. Also, it appears that the metabolism...
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Journal Articles
Journal: Dermatology
Dermatology (2005) 210 (Suppl. 1): 30–34.
Published Online: 11 February 2005
...B. Kasraee; C. Tran; O. Sorg; J.-H. Saurat Background: It has been known for a long time that the topical use of retinoic acid (RA) produces mild depigmentation of human skin. However, RA has two major disadvantages for its utilisation as a topical depigmenting compound. First, RA can act...
Journal Articles
Journal: Dermatology
Dermatology (2000) 200 (1): 40–42.
Published Online: 11 February 2000
... of a possible interference of indinavir with endogenous retinoid metabolism. Conclusion: Considerable evidence advocates the mediation of indinavir side effects by impaired oxidative metabolism of retinoic acid through the inhibition of cytochromes P450 3A by indinavir rather than by impaired formation of 9-cis...
Journal Articles
Journal: Dermatology
Dermatology (1999) 199 (Suppl. 1): 61–63.
Published Online: 12 August 1999
... compiled. Forty-five patients who had applied RAL on the face for 12–89 months were specifically examined for side-effects. Results: Studies in humans demonstrated an excellent tolerance of topical RAL on human skin. It was much better tolerated than retinoic acid and could be used even on sensitive facial...
Journal Articles
Journal Articles
Journal: Dermatology
Dermatology (1998) 197 (1): 1–5.
Published Online: 13 July 1998
... was detected at a constant level. Treatment of keratinocytes with Ca 2+ , a potent stimulator for cell differentiation, induced secretion of MMP-9, which was confirmed immunocytochemically. Inversely, treatment with retinoic acid, which inhibits cell differentiation, increased the level of MMP-2. Conclusion...