...Samer A. Dhaher; Jinan Q. Mohammed Introduction: Psoriasis is a chronic inflammatory systemic disease accompanied by systemic damage that leads to the development of multiple comorbidities including metabolic syndrome. Conventional systemic therapies for psoriasis are associated with toxicity...

...-to-severe psoriasis (PS), atopic dermatitis (AD), hidradenitis suppurativa (HS), or chronic urticaria (CU) starting or modifying a systemic treatment. At the inclusion visit and then every 6 months during 4 years, patient-reported outcomes and data on these diseases and their treatments are recorded...

... and various health conditions. However, there is limited data regarding its impact on psoriasis. The aim of our study was to compare psoriasis severity and the hormonal and immunological profile in patients with a night shift work to those with a daytime occupation. Methods: In this case-control study, we...

...Ana Ubago-Rodríguez; María I. Quiñones-Vico; Manuel Sánchez-Díaz; Raquel Sanabria-de la Torre; Álvaro Sierra-Sánchez; Trinidad Montero-Vílchez; Ana Fernández-González; Salvador Arias-Santiago Introduction: Psoriasis is a chronic inflammatory skin disease with variable clinical presentation...

...Hyun Ji Lee; Yong Jun Hong; Kyung Do Han; Ji Hyun Lee Introduction: As research on the role of the Th17/IL-23 pathway gains importance, the relationship between atopic dermatitis (AD) and psoriasis is becoming elucidated. Objective: The objective of this study wasto evaluate whether AD and its...

... was to investigate the agreement between consumer-driven self-assessed psoriasis severity and physician-assessed severity based on photographs. Methods: Customer IDs in the NØIE database (Danish skincare company) from 2009 to 2022 with a smartphone photograph of psoriasis vulgaris on the body and a corresponding...

...Weiwei Wu; Nan Gao; Junya Han; Yan Zhang; Xianfeng Fang Introduction: Psoriasis is a chronic immune-mediated skin disease. Several clinical trials have studied some topical drugs aiming at new therapeutic targets. However, the comparative efficacy and safety of different concentrations...

...Bjørn Kromann; Anna Olsson; Ying Marlene Zhang; Marianne Bengtson Løvendorf; Lone Skov; Beatrice Dyring-Andersen Background: Proteins play a central role in psoriasis as they are involved in the structural phenotypic changes and inflammation that characterize the disease. This systematic review...

...Yu Zhou; Kaihui Zhang; Xueting Ma; Zhiyin Xie Background: Secukinumab, a fully humanized monoclonal antibody against IL-17A, was approved for the treatment of moderate-to-severe plaque psoriasis in the USA and European Union in 2015. Objectives: Secukinumab, a fully humanized monoclonal antibody...

...Chin-Hsiao Tseng Background: Metformin’s effects on non-cancer skin diseases are rarely investigated. Objective: The aim of the study was to investigate immune-mediated (urticaria, allergic contact dermatitis, and psoriasis) and androgen-mediated (acanthosis nigricans, hidradenitis suppurativa...

...Catalina Hartmann Skovsgård; Trine Bay Laurberg; Anders Dige; Lars Iversen; Kasper Fjellhaugen Hjuler Background: Psoriatic arthritis (PsA) is a chronic inflammatory arthritis that occurs in a large proportion of patients with psoriasis causing pain and impaired quality of life. Early recognition...

...Teng-Li Lin; Ching-Min Kuo; Yi-Ling Chang; Hsiu J. Ho; Yi-Ju Chen; Chun-Ying Wu Background: Acitretin has been linked to the development of psychiatric disturbance. Objectives: The aim of this study was to assess the psychiatric hazards in patients with psoriasis prescribed acitretin compared...

.... Objectives: The objective of this study was to assess patients’ understanding of PsD, associated comorbidities, disease burden, and relationships with healthcare professionals (HCPs). Methods: Psoriasis and Beyond was a cross-sectional, quantitative online survey conducted in patients with a self-reported...

...Zheng Su; Yue-Ping Zeng Background: Dupilumab is the first approved IL-4Rα inhibitor for the treatment of atopic dermatitis at present with good efficacy and safety. However, there have been several reports of psoriasis and psoriasiform manifestations occurring after dupilumab therapy in recent...

...Zhijia Fan; Qiong Huang; Zhenghua Zhang; Ling Han; Xu Fang; Ke Yang; Guiqin Huang; Zhizhong Zheng; Nikhil Yawalkar; Yong Lin; Zhicheng Wang; Kexiang Yan Background: The study aimed to investigate the relationship of MAPK4 genetic variants with the efficacy of methotrexate (MTX) in psoriasis...

...), and strive to maximize the value created. Value in this context is defined as the health outcomes achieved per costs made. We have designed a lean IPU called PsoPlus in which psoriasis patients are managed by a multidisciplinary team which has all the expertise and skill to manage psoriasis and its...

...Siew Eng Choon; Mark G Lebwohl; Hamida Turki; Min Zheng; A. David Burden; Ling Li; Manuel Quaresma; Christian Thoma; Hervé Bachelez Background: Generalized pustular psoriasis (GPP) is a rare, neutrophilic skin disease that can become life-threatening if flares are untreated. There are limited data...

...) in patients with moderate-to-severe psoriasis. However, the clinical meaningfulness and predictive factors of CSC in daily practice have not yet been fully investigated. Objective: The study was conducted to, first, assess the impact of CSC on quality of life (QoL) improvements compared with treatment...

...: The objective of this study was to assess the long-term survival rates of adalimumab and infliximab in real-life practice. Methods: This study is based on data from the Turkish Psoriasis Registry and the digital records of the Medical School of Bezmialem Vakif University. Baseline data including demographic...

...Xiaoying Sun; Xiaoce Cai; Liu Liu; Hongjin Li; Yaqiong Zhou; Ying Luo; Yonghua Su; Bin Li; Xin Li Background: Psoriasis is a chronic recurrent inflammatory skin disease with a high risk of diabetes based on disease severity. Objectives: The aim of the study was to evaluate the efficacy of different...