...) and reflectance confocal microscopy (RCM) are ideal for this purpose. This study assessed clinically relevant statistical changes in RCM and OCT features in photoaged skin after light and energy-based therapy. Methods: Novel statistical analyses were performed using OCT and RCM data collected during a previously...

... of KPA (0.025%) to the dorsal skin of hairless mice enhanced collagen expression and attenuated UVB-induced Fn fragmentation and upregulation of MMP-2 and MMP-9 activities. Conclusions: Cathepsin G inhibitors may be useful for the prevention of UVB-induced photoaging through amelioration of ECM damage...

...M.C. Hughes; C. Bredoux; F. Salas; D. Lombard; G.M. Strutton; A. Fourtanier; A.C. Green Background: Dermal elastosis is considered the histological ‘gold standard’ for evaluation of skin photoaging, but the relation of the level of dermal elastosis to other histological indicators of photoaging...

...P. Creidi; Ph. Humbert Background: Retinaldehyde, the natural precursor of retinoic acid, should exert similar effects on photoaged skin. Objective: To establish the efficacy and safety of topical retinaldehyde on photoaged skin. Methods: Open and controlled clinical studies using image analysis...

...% retinaldehyde with an ex vivo technique using human skin in order to approximate in vivo metabolic conditions. Methods: Human skin explants were maintained alive in organ culture for 18 days and subjected to UVA exposure, thus simulating skin photoaging. Retinaldehyde cream was then applied to the surface...

..., instructions or products referred to in the content or advertisements. Retinaldehyde Photoaging Echography Elasticity Stiffness Skin thickness Chronological skin aging and chronic exposure to sunlight induce skin changes that are probably interrelated [ 1 ]. These include skin atrophy [ 2...