...Zhijia Fan; Qiong Huang; Zhenghua Zhang; Ling Han; Xu Fang; Ke Yang; Guiqin Huang; Zhizhong Zheng; Nikhil Yawalkar; Yong Lin; Zhicheng Wang; Kexiang Yan Background: The study aimed to investigate the relationship of MAPK4 genetic variants with the efficacy of methotrexate (MTX) in psoriasis...

...Zhijia Fan; Zhenghua Zhang; Qiong Huang; Ling Han; Xu Fang; Ke Yang; Siyuan Wu; Zhizhong Zheng; Nikhil Yawalkar; Zhicheng Wang; Kexiang Yan Background: There are great interindividual variations in the clinical efficacy of methotrexate (MTX) treatment and patients’ genetic background seems...

...Delphine Anuset; Geraldine Perceau; Philippe Bernard; Ziad Reguiai Background: In severe alopecia areata (AA), spontaneous recovery is unlikely, and treatment is not standardized. Ob jective: To evaluate the efficacy and safety of methotrexate (MTX) used alone or combined with low- to moderate-dose...

... progression. Oral minipulse therapy (OMP) with betamethasone/dexamethasone has been tried and shown to be an effective modality to arrest the disease progression in vitiligo. Objectives: Methotrexate (MTX) is a time-tested effective treatment extensively used in various autoimmune disorders with good efficacy...

... retrospective chart review of patients receiving FAEs was performed. Results: A total of 17 cases of patients receiving FAEs combined with at least one other systemic therapy (methotrexate, acitretin, etanercept, cyclosporine, leflunomide and infliximab) to treat psoriasis or psoriatic arthritis were identified...

... needs to be well established. Biologics Epidemiology Delphi process Methotrexate Psoriasis Psoriatic arthritis Rheumatology Systemic therapy © 2015 S. Karger AG, Basel 2015 Copyright / Drug Dosage / Disclaimer Copyright: All rights reserved. No part of this publication may...

...Oriol Yélamos; Alba Català; Eva Vilarrasa; Esther Roé; Lluís Puig Background: Methotrexate (MTX) is considered a relatively safe drug when prescribed at low-dose regimens not exceeding 25 mg/week. Severe acute toxicity is rare and presents with mucositis, cutaneous ulceration and pancytopenia. Most...

... was successfully and safely treated with methotrexate. We review the literature on HIV-related CD8+ pseudolymphoma and the use of methotrexate in HIV-positive patients. 2 08 2012 19 11 2012 22 1 2013 © 2013 S. Karger AG, Basel 2013 Copyright / Drug Dosage / Disclaimer Copyright: All...

...Catherine Droitcourt; Brigitte Milpied; Khaled Ezzedine; Thomas Hubiche; Emilie Belin; Fabrice Akpadjan; Alain Taïeb; Julien Seneschal Background: The combination of systemic pulse corticosteroids and methotrexate in the treatment of severe alopecia areata has never been reported. Objective...

...Jean-Hilaire Saurat; Annie Guérin; Andrew P. Yu; Dominick Latremouille-Viau; Eric Q. Wu; Shiraz R. Gupta; Yanjun Bao; Parvez M. Mulani Background: Methotrexate (MTX) and cyclosporine (CYC) may adversely interact with common medications in patients with psoriasis. Objective: Our purpose...

... successfully with etanercept (for 30 months) and then adalimumab (for 13 months and ongoing). Blanching was initially achieved with etanercept 50 mg twice a week, but suppression of periungual inflammation then required combination therapy with etanercept 50 mg twice a week and methotrexate 10 mg weekly; lower...

... with methotrexate. 40 biopsies were taken during treatment. A high incidence of pathological findings were found in both groups of psoriatics. Fatty metamorphosis, periportal inflammation, and focal necroses were found in statistically higher degree among psoriatics than among controls. It is suggested that besides...

...D.W.K. Cotton; Elisabeth van Rossum The kinetic constants of glucose-6-phosphate dehydrogenase from the blood of psoriatics with and without methotrexate therapy have been determined. The constants were also determined in the blood of normal subjects and subjects suffering from atopic dermatitis...

...E. Grunnet; A. Nyfors; Brogaard Hansen Ejaculates were studied from ten men with severe psoriasis treated with topical corticosteroids and from ten similar patients who had received methotrexate therapy from 1 to 9 years. It was not possible to demonstrate any unfavorable effect on the semen...

... acid to the dorsal ear surface of guinea pigs produced a progressive psoriasiform scaling which was apparent grossly and which could be quantitated. Triamcinolone acetonide, hydrocortisone and methotrexate, all known to be useful clinically in the treatment of psoriasis, were examined for their ability...

... to in the content or advertisements. Psoriasis Alcohol consumption Liver pathology Methotrexate Dermatológica 149: 136-139 (1974) Alcohol Consumption in Psoriasis E. G runnet Department of Dermatology, Marsellsborg Hospital, University of Arhus, Arhus Abstract. An investigation of drinking habits...

...D.W.K. Cotton; Elisabeth van Rossum The results of screening for 6-phosphogluconate dehydrogenase abnormalities in the blood of dermatological patients are reported. No differences were found between controls, psoriatics, psoriatics receiving methotrexate and a group of mixed patients. The results...

...S. Haim; Friedman Birnbaum This is a report on two cases with pemphigus vulgaris effectively controlled by dapsone. In one, dapsone was added to the treatment after a failure of combined prednisone and methotrexate therapy to control the disease completely. It is suggested that dapsone may offer...

...J.A. Newton; R.S. Camplejohn; C. Bowyer; D.H. McGibbon; N.A. Wright Epidermal cell proliferation in psoriasis was studied after oral methotrexate using tritiated uridine. Psoriatic enteropathy has in the past been reported to reduce the absorption of methotrexate administered orally but this study...

...Hans-Iver Beck; Erik K. Foged A case of toxic hepatitis caused by combination therapy with methotrexate and etretinate in the treatment of severe psoriasis is presented in a 47-year-old woman. The patient had received methotrexate alone for more than 10 years without any signs of severe liver...