.... Mast cells are a known component of cNFs. However, no comprehensive characterization of mast cells in cNFs is available, and their contributions to cNF growth and symptoms such as itch are not known. Methods: We collected 60 cNFs from ten individuals with NF1, studied their mast cell proteinase content...

... thresholds continued to be markedly reduced as compared to pre-desensitization levels (13.2 ± 8.2°C). Skin exposure to cold (ice cube, Temp Test ®) in cold urticaria patients resulted in pronounced cutaneous mast cell degranulation as assessed by skin microdialysis and subsequent histamine...

... Mast cells Fibroblasts 5 11 2009 © 1976 S. Karger AG, Basel 1976 Copyright / Drug Dosage / Disclaimer Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical...

.... We discuss Riccardi’s recent theory on the pathogenesis of neurofibroma which postulates that the mast cells have a primordial role in the development of neurofibroma. Our observation could be additional evidence in favor of this theory. 14 01 1983 15 01 1983 13 10 2009 © 1984 S...

... to in the content or advertisements. Urticaria pigmentosa Ketotifen Mast cells Dermatológica 706:44-47 (1983) © 1983 S. Karger AG. Basel 0011-9075/83/1661-0044S2.75/0 A Double-Blind Cross-Over Study of the Effect of Ketotifen in Urticaria pigmentosa Beate M. Czarnetzki Universitäts-Hautklinik Münster...

...Masashi Akiyama; Yonosuke Watanabe; Takeji Nishikawa The morphology of mast cells in the skin lesion from a case of urticaria pigmentosa was observed using light and electron microscopy. Furthermore, the IgE deposition on mast cells in the lesion was studied with immunoelectron microscopy...

... of steroids is the depletion of skin mast cells. This led to the treatment of patients with urticaria pigmentosa with topical high potency corticosteroids for 6 weeks. At the end of treatment there was a marked reduction in tissue histamine and an absence of mast cells as well as a disappearance of pruritus...

... revealed infiltrates of mast cells in the upper dermis. Ultrastructurally the mast cells were fully matured and exhibited no atypical features. A typical appearance of acromegaly, frontal bossing, prominence of the jaw and bony overgrowth and cutaneous changes of acanthosis nigricans on the neck...

...M. Nürnberger; I. Moll Mast cells are supposed to influence the growth of neurofibromas, because some of their mediators may also act as growth factors. Accordingly, mast cell stabilizers are claimed to reduce proliferation and itching of neurofibromas. Therefore, we quantified the mast cells of 19...

...B.M. Czarnetzki; B. Brechtel; O. Braun-Falco; E. Christophers; E. Schöpf; R. Reckers-Czaschka; M. Baudin; P. Dupuy Tiacrilast is a potent mast cell degranulation inhibitor in vitro and in animal studies. Since mast cells and their mediators are possibly involved in atopic eczema, we have studied...

... to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Psoriasis Mast cells Toluidin blue Immunohistochemistry against renal glomerular involvement in psoriatic patients with mod­ erate skin involvement. Although (3...

...A. Verzijl; R. Heide; A.P. Oranje; R.H.N. van Schaik Background: Mastocytosis is a heterogeneous group of disorders characterized by abnormal accumulation of mast cells. Objective: Skin biopsies from 24 patients (23 with proven mastocytosis) were screened for the presence of the c-kit Asp-816-Val...

... of the sebaceous glands in the skin from acne patients. Nerve growth factor showed immunoreactivity only within the germinative cells. In addition, an increase in the number of mast cells and a strong expression of endothelial leukocyte adhesion molecule-1 on the postcapillary venules were observed in adjacent...

... and nonlesional skin were statistically significant. Double immunostaining revealed that IL-13 was produced in approximately 40% of T cells and 20% of mast cells in AD lesional skin, suggesting that T cells and mast cells are major sources of IL-13 in AD lesions. Conclusion: IL-13 may play a local as well...

... in the skin from dorsal root ganglia or immune cells. CRH typically acts through activation of specific receptors that are either type 1 or types 2α and 2β. CRH, or related peptides such as urocortin, could have proinflammatory effects directly or through activation of mast cells leading to destruction...