...Yiwen Li; Patrick Speck; Eric Viera; Meron Siira; Lauren A.V. Orenstein Background: Pain and itch are impactful and burdensome symptoms of hidradenitis suppurativa (HS). Elucidating factors associated with pain and itch severity may identify groups disproportionally affected by HS-related pain...

... to in the content or advertisements. Key Message This study provides data on adult use and care for prurigo and pruritus in Germany. Chronic prurigo Chronic pruritus Itch Healthcare utilization Treatment patterns Chronic prurigo is a skin condition that poses significant challenges...

... diseases. Itch Pain Paresthesia Skin Pruritus is the main symptom reported in dermatological diseases and is defined as an unpleasant sensation that provokes the need to scratch [1, 2]. Pruritus is included in the definition of some dermatoses, such as atopic dermatitis (AD) or urticaria...

...Nazgol-Sadat Haddadi; Saeed Shakiba; Khashayar Afshari; Arvin Haj-Mirzaian; Sara Vesaghati; Saber Gharagozlou; Roham Foroumadi; Hamed Shafaroodi; Sattar Ostadhadi; Ahmad Reza Dehpour Background: Metformin ameliorates non-histamine-mediated itch. We have recently reported that the nitric oxide...

... HRQoL in relation to age, gender, skin lesions (primary vs. scratch-induced secondary) and itch intensity. Methods: Consecutive patients of our itch clinic were assessed with the Dermatology Life Quality Index (DLQI) and visual analogue scale (VAS). Results: In 510 CP patients (282 females; median age...

...Linda Ruppert; Christian Apfelbacher; Sonja Molin; Andrea Bauer; Vera Mahler; Jochen Schmitt; Peter Elsner; Thomas L. Diepgen; Elke Weisshaar Background: Itching is a leading symptom of chronic hand eczema (CHE) having a great impact on patients. The determinants of itching in CHE are unclear...

... or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Chronic pruritus Itch Therapy...

.... Given that multiple therapy steps produce a high disease and economic burden, novel target-specific therapies are eligible. Chronic pruritus, which is defined as itch lasting for longer than 6 weeks, occurs in up to 23% of all adults and is a frequent symptom in many medical specialities [ 1,2 ]. Up...

... correlated only weakly with pruritus intensity (R = 0.11). The most afflicted areas were the extremities followed by trunk and head/neck. The whole body was affected in 16%. Half of the affected participants stated that they had suffered from itching for at least 1 year, a quarter for >5 years. 40...

... to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Asthma Atopic dermatitis features Cataract Dennie-Morgan infraorbital fold IgE Food intolerance Xerosis Itch Clinical and Laboratory Investigations Dermatology 1994...

...Laurent Misery Pruritus is not the equivalent of the cough of the skin, but itch and scratch can certainly be defined as such. In physiological conditions, they share the same function: to exclude a foreign body. Itch/scratching and cough could be selective responses for the same diseases, mainly...

...Florence Dalgard; Aerlyn G. Dawn; Gil Yosipovitch Background: Few large-scale epidemiological studies have been performed on the prevalence of itch. Itch and pain are common and complex symptoms which contribute to the burden of disease. Although there is antagonistic interaction between itch...

...’ and ‘pattern’ hypothesis, we propose a new theory especially for histamine-unrelated, peripheral induction of chronic pruritus. We suggest that ‘itch’ is elicited in the epidermal unmyelinated nerve C-fibers and ‘pain’ in the dermal unmyelinated nerve fibers. The downregulation of the opioid receptor...