... for refractory discoid lupus erythematosus (DLE) in 1983 and has steadily grown since then. Method: In this review, we describe the therapeutic benefits of thalidomide for DLE treatment and its biological properties. We explain how new discoveries in DLE pathogenesis are relevant to understand thalidomide’s...

... for ED was defined as ΔED. The ED of each photograph was calculated using ImageJ® plug-in color deconvolution. Lupus erythematosus tumidus Chronic cutaneous lupus erythematosus Computer-aided image analysis Discoid lupus erythematosus Jessner’s lymphocytic infiltration of the skin...

...Gunver Risum In 54 patients with lupus erythematosus – 6 with systemic, 19 with disseminated discoid, and 29 with localized discoid lupus erythematosus determination of the 3rd and 4th components of complement (C3 and C4) was performed in a prospective study. In relation to 42 healthy persons...

...Fuad S. Farah; Mona T. Matta; Shukrallah Zeinoun; Samir I. Shehadeh The association of discoid lupus erythematosus (DLE) and solar keratosis, squamous cell carcinoma, and keratoacanthoma in three different subjects prompted the study of the histologic changes in DLE. Seventy-one biopsies were...

...S. Jablonska; T. Chorzelski; W. Mazurkiewicz The paper describes a case corresponding clinically and histologically to annular atrophic plaques of the face and resembling lichen sclerosus et atrophicus, morphea, and discoid lupus erythematosus (DLE). Immunopathological investigations were twice...

...Rune Lindskov; Flemming Reymann Thirty-three patients with chronic discoid lupus erythematosus (DLE) who had received dapsone for 1–27 months were reviewed. The dapsone treatment gave excellent results in 8 patients (24%), some effect in 8 patients (24%), while no response was seen in 17 patients...

...Flemming da Cunha Bang; Gunhild Lange Wantzin; Jens Dahl Christensen A 24-year-old woman with discoid lupus erythematosus developed systemic lupus erythematosus after 6 years. One of the clinical features was Raynaud’s phenomenon in the fingers and toes, and furthermore Raynaud’s phenomenon...

...Rune Lindskov; Jan Mikael Munkvad; Niels Henrik Valerius Discoid lupus erythematosus (DLE)-like lesions and recurrent aphthous-like stomatitis have often been described in carriers of X-linked chronic granulomatous disease (CGD). The capacity of the polymorphonuclear leucocytes to reduce nitroblue...

...Giancarlo Chieregato; Alberto Peroni; Luca Castellani; Michele A. Nigro Ten cases of localized and generalized discoid lupus erythematosus are reported in which previously untreated patients were given hydroxychloroquine sulphate 600 mg daily for 10 days followed by 400 mg for 20 days. The purpose...

...T. Sasaki; H. Nakajima Six patients with systemic sclerosis (SS) and discoid lupus erythematosus (DLE) were studied to determine whether such cases have some common clinical and laboratory findings. DLE preceded SS in all cases. Three patients had diffuse scleroderma with lung and esophagus...

...Atsuko Adachi; Hiroshi Nagai; Tatsuya Horikawa Background: It is well known that fluorouracil (FU) agents frequently induce discoid-lupus-erythematosus (DLE)-like eruptions and acral erythema in Japan. However, the etiology of these drug eruptions caused by FU agents has not been clarified yet...

...(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Acitretin Side-effects Rectal bleeding Discoid lupus erythematosus Correspondence and Opinions In this issue Rectal...

...Hélio Amante Miot; Luciane Donida Bartoli Miot; Gabriela Roncada Haddad Background: Discoid lupus erythematosus (DLE) is a chronic cutaneous disease affecting photoexposed areas and has also been associated with cigarette smoking. Objective: To evaluate the association between smoking and DLE...

.... Contact dermatitis, urticaria and oedemas of cardiac or renal origin are among the most common causes. We here report a case of a 74-year-old patient with a history of discoid lupus erythematosus (DLE), who developed periorbital oedema and erythema after systemic treatment for DLE had been stopped...

...Somesh Gupta Background: Longstanding lesions of discoid lupus erythematosus (DLE) may heal with thin, depigmented scar(s). The depigmentation may fail to respond to medical therapies. Objective: To evaluate the efficacy of suction blister epidermal grafting in longstanding, quiescent, depigmented...

...Annegret Kuhn; Petra Maria Becker-Wegerich; Thomas Ruzicka; Percy Lehmann Vascular lesions with telangiectasias on visible areas, such as the face, are common in discoid lupus erythematosus (DLE); however, an efficient management of these skin lesions can sometimes be difficult. Since argon laser...