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Keywords: Cytotoxic T lymphocytes
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Journal Articles
Journal Articles
Journal: Dermatology
Dermatology (2001) 202 (3): 198–202.
Published Online: 23 May 2001
... antigen (TIA-1) and granzyme B (GrB). TIA-1 labels cytotoxic granules of resting and activated T cells, whereas GrB designates activated cytotoxic T lymphocytes (CTL). Results: In all cases, numerous T cells were consistently found expressing cytotoxic granules. The results indicated a high number...
Journal Articles
Journal: Dermatology
Dermatology (2001) 202 (2): 94–98.
Published Online: 09 April 2001
... by cytotoxic T lymphocytes (CTL). Objective: To elucidate the role of CTL in the mechanism of epidermal injury in GVHD. Methods: We studied immunohistochemical staining for granzyme B and perforin in the skin lesions of 8 patients who developed GVHD after bone marrow transplantation. Results: Granzyme-B...