...S.R. Shukla 20 patients with vitiligo were treated with 100 mg of clofazimine daily. Half of these cases were exposed to sunlight and the remaining cases were given no sun exposure. After 3 months of therapy, repigmentation of lesions was seen in 2 cases only, 1 in each group. Sun exposure had...

... reaction in the dermis with abscess formation and tissue destruction. There was no evidence of blood vessel inflammatory changes. The course of the disease was characterized by marked chronicity and partial response to systemic steroid and antibiotic therapy. Treatment with clofazimine resulted in a marked...

...Ronald Anderson; Birgit M. Zeis; Ingram F. Anderson Clofazimine, at concentrations within the therapeutic range (0.01–5 μg/ml), stimulated human polymorphonuclear leucocytes (PMNL) to generate increased amounts of reactive oxidants (RO) when activated with the tripeptide leucoattractant N-formyl- L...

...Hartwig Mensing Five patients suffering from dermatitis ulcerosa (a variant of pyoderma gangrenosum) were treated with clofazimine in a daily dosage of 200 mg orally. Complete healing was noted in 2 patients, partial response in 2, no effect in 1. Side effects were mild and transitory in form...

.... The topical group includes agents such as sulfur, salicylic acid and the alpha-hydroxy acids, while the systemic group includes diaminodiphenylsulfone, clofazimine, ibuprofen and others. Some presumably useful physical methodologies and the recent findings in phototherapy, particularly the properties of blue...