...) for pharmacological studies. In this study, LDF monitoring of the physiological skin response to histamine was made in a randomized, placebo-controlled, double-blind study comparing the in vivo anti-H 1 activity of cetirizine (10 mg) or loratadine (10 mg), 6 h after a single oral intake. As compared with responses...

...J.-P. Rihoux; L. Ghys; K. Mühlethaler; B. Wüthrich Two double-blind clinical pharmacology studies were performed in atopies in order to compare the inhibitory effects of cetirizine (CTZ) 2 HCl and terfenadine (TER) on histamine and antigen-induced skin reactions. In the first study, the subjects...

...J. Rivest; K. Despontin; L. Ghys; J.P. Rihoux; J.M. Lachapelle The peripheral H 1 -inhibiting effects of cetirizine 10 mg and ebastine 10 mg were compared at the skin level after single oral administration. The study was performed in 9 healthy subjects under double-blind randomized cross-over...

...J. de la Cuadra; M. Teruel; P. Teixidó; J. Roma In order to assess the antihistaminic power of cetirizine and ebastine, we designed a randomized, double-blind, crossover study, measuring their capacity to modify skin blood flow induced by a histamine prick test. The vasomotor response was compared...

... advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Adverse drug reaction Cetirizine...

...Giuseppe Monfrecola; Elvira Masturzo; Anna Maria Riccardo; Antonio Del Sorbo After 15 days of orally administered cetirizine a 2- to 6-fold increase in MUD was observed in all patients; after 15 days of combined treatment (oral cetirizine + sun exposure) a 3.5- to 10-fold increase in MUD values...

... with this method have shown histamine-induced laser Doppler changes in the wheal area. Objective: In order to compare the influence of two H 1 receptor antagonists (cetirizine 10 mg vs. ebastine 10 mg) on the skin vascular responses to histamine introduced by iontophoresis, we designed a double-blind, randomized...