...Ayse Boyvat; Ayse Oktem; Incilay Kalay Yildizhan; Askın Ates; Nilufer Yalcindag; Cuneyt Koksoy; Canan Yucesan Background: Previous reports indicate that juvenile Behçet’s disease (BD) may have a different course than adult BD. However, as a direct comparison with adult Behçet patients has only been...

...Jin Hyung Jung; Kyung Do Han; Young Bok Lee; Yong Gyu Park Background: No epidemiologic study has previously reported on the associations among Behçet’s disease (BD) and autoimmune disorders. Objectives: To investigate the association between BD and the autoimmune disorders multiple sclerosis...

...Aristeidis G. Vaiopoulos; Meletios A. Kanakis; Violetta Kapsimali; Georgios Vaiopoulos; Phedon G. Kaklamanis; Christos C. Zouboulis Adamantiades-Behçet disease (ABD) is a chronic, multisystemic, recurrent, inflammatory vascular disorder of unknown etiology. Patients with symptoms initially...

...Antonio Vitale; Donato Rigante; Francesco Caso; Maria Giuseppina Brizi; Mauro Galeazzi; Luisa Costa; Rossella Franceschini; Orso Maria Lucherini; Luca Cantarini Recommendations related to ocular, mucosal and cutaneous involvement of Behçet's disease (BD) are mainly evidence-based, but in cases...

.... Behçet’s disease Chronic active Epstein-Barr virus infection Epstein-Barr virus Hydroa vacciniforme Orogenital ulcer Chronic active Epstein-Barr virus (EBV) infection is a type of lymphoproliferative disorder caused by reactivation of latent EBV infection. Patients with this disorder present...

... activation and IL-1β production are important in HS. Colchicine is efficacious in the IL-1β- and inflammasome-mediated diseases gout, familial Mediterranean fever and Behçet’s disease, and therefore a potentially effective drug in HS. Objective: To investigate the efficacy of colchicine in HS. Methods...

...J.D. Sobel; S. Haim; A. Shafrir; B. Gellei Ten patients with active Behçet’s disease were studied to evaluate whether the cutaneous response to intracutaneous injection of autologous plasma differs from those known to occur in the disease following needle prick and injection of normal saline...

...J.D. Sobel; S. Tabori; I. Tatarski Venous thrombosis, including superior and inferiorvena caval occlusion is considered an integral manifestation of Behçet’s disease. In this series, 5 of 11 patients (45.4%) with active Behçet’s disease had clinical evidence of present or past venous thrombosis...

...S. Haim The etiology and treatment of Behçet’s diseases are still undecided. There are three principal etiological hypotheses: viral, autoimmune and defective fibrinolytic activity. Accordingly, antiviral, immunosuppressive and fibrinolytic enhancing agents have been tried. Corticosteroids, however...

...S. Haim; T. Mekori; J.D. Sobel; E. Robinson Aspects of lymphocyte function were investigated, in vitro, in nine patients with active Behçet’s disease. The rosette formation technique revealed a slight decrease in number of T lymphocytes and more so of B lymphocytes. In spite of their low number...

...S. Haim Current concepts incriminate a cell-mediated mechanism in the pathogenesis of mucocutaneous lesions of Behçet’s disease. However, such a mechanism alone fails to explain various aspects of hyperreactivity response which is a unique feature manifested with lesions similar to those occurring...

...Taiichi Saito; Takayoshi Honma; Keiya Saigo The number of Langerhans’ cells (LHC) in the prickle cell layer was increased after prick test in patients with Behçet’s disease. LHC came into contact with lymphocytes in the prickle cell layer. Lattice-shaped granules were seen in the mitochondria...

...C. Lichtig; S. Haim; A. Gilhar; I. Hammel; R. Ludatscher In order to assess the role of mast cells in the pathogenesis of mucocuta-neous lesions of Behçet’s disease, the following investigations were performed: (1) a comparative study of ultrastructural features of mast cells in sopntaneous...

...S. Haim; A. Gilhar; T. Mekori; R. Segal The leucocyte migration inhibition (LIF) was investigated in 16 patients with Behçet’s disease, 5 while in the active stage of the process, 3 both during relapse and remission, and 8 during remission of symptoms. In all patients skin tests with various...

...M. Nahir; Y. Scharf; O. Gidoni; A. Barzilai; R. Friedman-Birnbaum; S. Haim Histocompatibility antigens (HL-A) were studied in a family with Behçet’s disease (BD). All who had symptoms or signs of BD had either HL-A B5 or BW35, or both. 18 07 1977 15 08 1977 14 10 2009 © 1978 S...

...D. Djawari; O.P. Hornstein; L. Luckner Comparative in vivo examinations of skin (cutaneous pathergy test, skin window technique over 24 h according to Rebuck) were carried out in 12 patients with Behçet’s disease (BD) and in 13 healthy volunteers serving as controls. 10 out of 12 patients at active...

...G. Reimer; L. Luckner; O.P. Hornstein Direct immunofluorescence (IF) investigations in oral aphthae were performed in 17 patients with recurrent aphthous ulcers (RAU) and in 9 patients with Behçet’s disease (BD). In addition, cutaneous hyperreactivity lesions from 2 BD patients were examined...

... patients with Behçet’s disease (Touraine’s aphthosis). A major improvement was noted in all groups, with a rapid healing of mucous lesions and a rapid reduction of pain and burning as compared to prior spontaneous regressions. No new outbreaks were noted at a dose of 50–100 mg thalidomide and 1 mg...

...M. Çalgüneri; İ. Ertenli; S. Kiraz; M. Erman; İ. Çelik Background : Recent studies point out a probable role of streptococcal antigens in the pathogenesis of Behçet’s disease (BD). This has led to the proposal of benzathine penicillin as a therapeutic modality in BD. Objective : A prospective study...

...G. Azizlerli; V.L. Aksungur; R. Sanca; E. Akyol; C. Övül The HLA-B5 phenotype was investigated in 235 patients with Behçet’s disease and in 100 healthy persons. HLA-B5 was more frequent in the patients (77 vs. 30% p < 0.001, relative risk = 7.8). The frequency of HLA-B5 was higher in patients...