...R. Laurent; P. Agache An ultrastructural study of the dermis in a case of acrogeria is presented and compared with a healthy control of same age and sex. The overgrowing orceinophil material was mainly pseudoelastic. The collagen was hypoplastic and mostly immature. Inside and outside...

...A. Hjortshøj; G. Heydenreich A case of acrogeria in a 12-year-old girl is reported. Acrogeria is a rare, non-hereditary, probably congenital disease of which the main characteristic is an atrophy of the skin giving it an aged appearance. The defect is localized to the dermis and subcutis, whereas...

...Akira Konohana; Shunichi Miyakawa; Shingo Tajima; Takeji Nishikawa Biochemical analysis of involved and uninvolved skin of a 16-year-old female with acrogeria showed that hyaluronic acid and collagen contents were decreased only in involved skin. Explant cultures from both involved and uninvolved...

...L. Bruckner-Tuderman; A. Vogel; U.W. Schnyder An 11-year-old patient with clinically typical acrogeria is presented. She had wrinkled ‘old-appearing’ acral skin, thin skin on the whole integument, grooved tip of nose, mottled hyperpigmentation of fold regions and thickened dystrophic toe nails...

...S. Tajima; T. Inazumi; T. Kobayashi We report a case of acrogeria. Biochemical analysis of patient fibroblasts demonstrated unaltered type III collagen synthesis. An RNA hybridization assay demonstrated that the levels of type I and elastin mRNAs were normal. The patient had multiple yellow papules...