Background: The skin hyperpigmentation index (SHI), a new objective method for measuring skin hyperpigmentation, needs validation. Objective: To gain evidence of the reliability and validity of the SHI. Methods: Fifteen raters were divided into 3 groups (5 dermatologists, 5 nondermatologist physicians, and 5 nonphysician clinicians). Each rated 5 pigmented mole lesions with mild-to-severe hyperpigmentation to determine intra- and interrater reliability. All raters photographed the lesions and rated them using the subjective Physician Global Assessment (PGA) score. The same photographs were then assessed based on automatic computer measurement software using the online SHI tool (https://shi.skinimageanalysis.com). Results: The SHI reliability was excellent for all intra- and interrater assessments, while most PGA assessments showed good intra- and interrater agreement. Between-group reliability was excellent for SHI, while moderate-to-good for PGA evaluations. Concordance between the SHI and PGA assessments was strong across all groups of assessors. Conclusion: There is evidence that the SHI is a reliable instrument for measuring skin hyperpigmentation, and can be used by nonexperienced clinicians.

Keywords:
Skin hyperpigmentation index, Physician Global Assessment Score, Hyperpigmentation, Pigmentation
1.
Kumaran
 
MS
,
Dabas
 
G
,
Vinay
 
K
,
Parsad
 
D
.
Reliability assessment and validation of the dermal pigmentation area and severity index: a new scoring method for acquired dermal macular hyperpigmentation
.
J Eur Acad Dermatol Venereol
.
2019
;
33
(
7
):
1386
–
92
.
Google Scholar
Crossref
Search ADS
PubMed
 
2.
Bossart
 
S
,
Cazzaniga
 
S
,
Willenberg
 
T
,  
Skin hyperpigmentation index: a new practical method for unbiased automated quantification of skin hyperpigmentation
.
J Eur Acad Dermatol Venereol
.
2020
;
34
(
7
):
e334
–
6
.
Google Scholar
Crossref
Search ADS
PubMed
 
3.
Bossart
 
S
,
Ramelet
 
AA
,
Willenberg
 
T
,  
Skin hyperpigmentation index facilitating quantification of hyperpigmentation in clinical practice
.
Dermatology
.
2021
;
237
(
3
):
486
–
8
.
Google Scholar
Crossref
Search ADS
PubMed
 
4.
Bossart
 
S
,
Willenberg
 
T
,
Ramelet
 
AA
,
Cazzaniga
 
S
,
Hunger
 
RE
,
Seyed Jafari
 
SM
.
The skin hyperpigmentation index: an objective method of measuring the intensity of hyperpigmentation after sclerotherapy
.
Phlebology
.
2020 Dec
;
35
(
10
):
833
–
5
.
Google Scholar
Crossref
Search ADS
PubMed
 
5.
McGraw
 
KO
,
Wong
 
SP
.
Forming inferences about some intraclass correlation coefficients
.
Psychol Methods
.
1996
;
1
(
1
):
30
–
46
.
Google Scholar
Crossref
Search ADS
 
6.
Guo
 
CC
,
Kurth
 
F
,
Zhou
 
J
,  
One-year test-retest reliability of intrinsic connectivity network fMRI in older adults
.
Neuroimage
.
2012
;
61
(
4
):
1471
–
83
.
Google Scholar
Crossref
Search ADS
PubMed
 
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