Background: Alopecic and aseptic nodule of the scalp (AANS) is a rare disease entity first reported in 1992 as pseudocyst of the scalp (PCS). Controversy exists regarding the histopathology and etiology of reported cases. Objective: We performed this study to analyze the clinical and histopathologic features of AANS/PCS in Korean patients. Methods: A retrospective review of medical records from 2008 to 2013 at Inje University Busan Paik Hospital was performed. Results: Eleven patients were enrolled. All patients were male, and their mean age was 21.6 years. Most patients had a solitary nodule (10/11) located predominantly on the vertex. The mean nodule size was 20 mm. Inflammatory cell infiltration in the deep dermis was a histologic feature of AANS/PCS. Eight patients showed granulomatous infiltration. All patients were treated with short-term antibiotics and intralesional steroid injection. Conclusion: Our results suggest that dermatologists should consider AANS when diagnosing an alopecic nodule on the scalp.

1.
Iwata T, Hashimoto T, Niimura M: A pseudocyst with inflammatory granulation tissue on scalp - pseudocyst of scalp. Jpn J Clin Dermatol 1992;46:9-16.
2.
Abdennader S, Reygagne P: Alopecic and aseptic nodules of the scalp. Dermatology 2009;218:86.
3.
Chevallier J: Abcès non infectieux et alopéciques du cuir chevelu: nouvelle entité? Nouv Dermatol 1998;17:181.
4.
Tsuruta D, Hayashi A, Kobayashi H, Nakagawa K, Furukawa M, Ishii M: Pseudocyst of the scalp. Dermatology 2005;210:333-335.
5.
Abdennader S, Vignon-Pennamen MD, Hatchuel J, Reygagne P: Alopecic and aseptic nodules of the scalp (pseudocyst of the scalp): a prospective clinicopathological study of 15 cases. Dermatology 2011;222:31-35.
6.
Lee SS, Kim SY, Im M, Lee Y, Seo YJ, Lee JH: Pseudocyst of the scalp. Ann Dermatol 2011;23:S267-S269.
7.
Eisenberg EL: Alopecia-associated pseudocyst of the scalp. J Am Acad Dermatol 2012;67:e114-e116.
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