Various diseases of pigmentation in the newborn are known, such as congenital or acquired linear hyperpigmentation. Pigmentary lines of the newborn are counted among the transient benign cutaneous lesions in the newborn and appear to be rather rare. This paper reports on a newborn with pigmentary lines in the creases of the abdomen. The 5-month-old boy is the first case observed so far in the University Hospital of Basel in Switzerland. He was born at term and healthy, without any congenital abnormalities. The horizontally arranged linear hyperpigmentation appeared shortly after birth and faded spontaneously after 5 months. Pigmentary lines of the newborn are rare and the non-hormonal cause may be flexion in utero or other mechanically induced stimulation. So far, only eight similar cases have been reported, which are listed in a table.

1.
Fistarol SK, Itin PH: Disorders of pigmentation. J Dtsch Dermatol Ges 2010;8:187-201.
2.
Tagra S, Talwar AK, Walia RL: Lines of Blaschko. Indian J Dermatol Venereol Leprol 2005;71:57-59.
3.
Molho-Pessach V, Schaffer JV: Blaschko lines and other patterns of cutaneous mosaicism. Clin Dermatol 2011;29:205-225.
4.
Happle R: X-chromosome inactivation: role in skin disease expression. Acta Paediatr Suppl 2006;95:16-23.
5.
Happle R: Spuren der Frühzeit: embryologische Verteilungsmuster bei Hauterkrankungen; in Fortschritte der praktischen Dermatologie und Venerologie, Vol. 17. Berlin/Heidelberg, Springer, 2001, pp 128-136.
6.
James WD, Meltzer MS, Guill MA, Berger TG, Rodman OG: Pigmentary demarcation lines associated with pregnancy. J Am Acad Dermatol 1984;11:438-440.
7.
James WD, Carter JM, Rodman OG: Pigmentary demarcation lines: a population survey. J Am Acad Dermatol 1987;16:584-590.
8.
Lucky AW: Transient benign cutaneous lesions in the newborn; in Eichenfield LF, Frieden IJ, Esterly NB (eds): Textbook of Neonatal Dermatology. Philadelphia, WB Saunders Company, 2001, pp 96-97.
9.
Monteagudo B, León-Muiños E, Suárez-Amor O, Labandeira J: Transient pigmentary lines of the newborn. Actas Dermosifiliogr 2013;104:537-539.
10.
Martín JM, Jordá E, Alonso V: Transient pigmentary lines of the newborn. Pediatr Dermatol 2009;26:768.
11.
Garg G, Bhalla M, Thami GP: Transient infantile patterned hyperpigmentation. Pediatr Dermatol 2012;29:372-373.
12.
Gibbs RC: Unusual striped hyperpigmentation of the torso. A sequel of abnormalities of epitrichial exfoliation. Arch Dermatol 1967;95:385-386.
13.
Halper S, Rubenstein D, Prose N, Levy ML: Pigmentary lines of the newborn. J Am Acad Dermatol 1993;28:893-894.
14.
Prigent F, Aufrant C, Bombard Y: Pigmentation linéaire du noveau-né. Arch Pediatr 2000;7:1316-1317.
Copyright / Drug Dosage / Disclaimer
Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher.
Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.
You do not currently have access to this content.