Abstract
Accumulative evidence supports the role of nutritional factors in acne. I report here 5 healthy male adult patients developing acne after the consumption of whey protein, a favorite supplement of those engaged in bodybuilding. These observations are in line with biochemical and epidemiological data supporting the effects of milk and dairy products as enhancers of insulin/insulin-like growth factor 1 signaling and acne aggravation. Further prospective studies are required to determine the possible role of dietary supplements in the fitness and bodybuilding environment.
References
1.
Williams HC, Dellavalle RP, Garner S: Acne vulgaris. Lancet 2012;379:361–372.
2.
Simonart T: Newer approaches to the treatment of acne. Am J Clin Dermatol 2012; 13:357–364.
3.
Veith WB, Silverberg NB: The association of acne with diet. Cutis 2011;88:84–91.
4.
Di Landro A, Cazzaniga S, Parazzini F, Ingordo V, Cusano F, Atzori L, Cutrì FT, Musumeci ML, Zinetti C, Pezzarossa E, Bettoli V, Caproni M, Lo Scocco G, Bonci A, Bencini P, Naldi L, GISED Acne Study Group: Family history, body mass index, selected dietary factors, menstrual history, and risk of moderate to severe acne in adolescents and young adults. J Am Acad Dermatol 2012;67:1129–1135.
5.
Adebamowo CA, Spiegelman D, Berkey CS, Danby FW, Rockett HH, Colditz GA, Willett WC, Holmes MD: Milk consumption and acne in teenaged boys. J Am Acad Dermatol 2008;58:787–793.
6.
Cordain L, Lindeberg S, Hurtado M, et al: Acne vulgaris: a disease of Western civilization. Arch Dermatol 2002;138:1584–1590.
7.
Smith RN, Mann NJ, Braue A, et al: The effect of a high-protein, low glycemic-load diet versus a conventional, high glycemic-load diet on biochemical parameters associated with acne vulgaris: a randomized, investigator-masked, controlled trial. J Am Acad Dermatol 2007;57:247–256.
8.
Danby FW: Nutrition and acne. Clin Dermatol 2010;28:598–604.
9.
Kwon HH, Youn JY, Hong JS, Jung JY, Park MS, Suh DH: The clinical and histological effect of low glycemic load diet in the treatment of acne vulgaris in Korean patients: a randomized, controlled trial. Acta Derm Venereol 2012;92:241–246.
10.
Krissansen GW: Emerging health properties of whey proteins and their clinical implications. J Am Coll Nutr 2007;26:713S–723S.
11.
Silverberg NB: Whey protein precipitating moderate to severe acne flares in 5 teenaged athletes. Cutis 2012;90:70–72.
12.
Haug A, Hostmark AT, Harstad OM: Bovine milk in human nutrition – a review. Lipids Health Dis 2007;6:25.
13.
Melnik BC: Evidence for acne-promoting effects of milk and other insulinotropic dairy products. Nestle Nutr Workshop Ser Pediatr Program 2011;67:131–145.
14.
Melnik BC: Dietary intervention in acne. Dermatoendocrinology 2012;4:20–32.
15.
Kim J, Ko Y, Park YK, Kim NI, Ha WK, Cho Y: Dietary effect of lactoferrin-enriched fermented milk on skin surface lipid and clinical improvement of acne vulgaris. Nutrition 2010;26:902–909.
16.
Mueller EA, Trapp S, Frentzel A, Kirch W, Brantl V: Efficacy and tolerability of oral lactoferrin supplementation in mild to moderate acne vulgaris: an exploratory study. Curr Med Res Opin 2011;27:793–797.
17.
Goldfield GS, Woodside DB: Body image, disordered eating, and anabolic steroids in male bodybuilders: current versus former users. Phys Sportsmed 2009;37:111–114.
18.
Tsai MC, Chen W, Cheng YW, Wang CY, Chen GY, Hsu TJ: Higher body mass index is a significant risk factor for acne formation in schoolchildren. Eur J Dermatol 2006;16:251–253.
19.
Melnik B, Jansen T, Grabbe S: Abuse of anabolic-androgenic steroids and bodybuilding acne: an underestimated health problem. J Dtsch Dermatol Ges 2007;5:110–117.
© 2012 S. Karger AG, Basel
2012
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