Background: Hypertrichosis following cast application is commonly observed after removing casts, due to an unknown mechanism. Objective: To determine the frequency and associated demographic and clinical risk factors of postcast hypertrichosis in patients who underwent cast application for bone fractures. Methods: The study included 117 patients (50 females, 67 males, age range: 3–91 years). Demographic information of each patient (age, gender, fracture localization, type of cast, cast duration and pruritus) was recorded. After removing the cast, the presence of hypertrichosis, contact dermatitis and lymphedema of the cast area was evaluated. Demographic and clinical features of the patients were analyzed to determine the risk factors for postcast hypertrichosis. Results: Postcast hypertrichosis was detected in 34.2% of patients. Patients with hypertrichosis were younger than those without hypertrichosis (p = 0.015). Duration of cast application, session of cast application, presence of lymphedema, contact dermatitis and pruritus between patients with hypertrichosis and without hypertrichosis were similar (p > 0.05). Age was the only parameter independently associated with developing postcast hypertrichosis (OR: 0.97, 95% CI: 0.95–0.99; p = 0.008). The frequency of hypertrichosis peaked significantly between 12 and 25 years (p = 0.026). Conclusion: A significant number of patients with cast application developed hypertrichosis. Patient age was closely associated with postcast hypertrichosis.

1.
Wendelin DS, Pope DN, Mallory SB: Hypertrichosis. J Am Acad Dermatol 2003;48:161–179.
2.
Bertolino AP, Freedberg IM: Hair; in Fitzpatrick TB, Eisen AZ, Wolff K, Freedberg IM, Austen KF (eds): Dermatology in General Medicine. New York, McGraw-Hill, 1993, pp 671–696.
3.
Krause K, Foitzik K: Biology of the hair follicle: the basics. Semin Cutan Med Surg 2006;25:2–10.
4.
Olsen EA: Hypertrichosis; in Olsen EA (ed): Disorders of Hair Growth: Diagnosis and Treatment. New York, McGraw-Hill, 1993, pp 315–336.
5.
Pick RY: Focal hair growth under plaster-of-Paris cast. NY State J Med 1980;80:1726.
6.
Bergen D: Localized hirsutism following Colle’s fracture. Can Med Assoc J 1983;128:368.
7.
Nielsen JS: Localized hirsutism following Colles’ fractures. Can Med Assoc J 1983;129:229.
8.
Harper MC: Localized acquired hypertrichosis associated with fractures of the arm in young females. A report of two cases. Orthopedics 1986;9:73–74.
9.
Leung AK, Kiefer GN: Localized acquired hypertrichosis associated with fracture and cast application. J Natl Med Assoc 1989;81:65–67.
10.
Chang CH, Cohen PR: Ipsilateral post-cast hypertrichosis and dyshidrotic dermatitis. Arch Phys Med Rehabil 1995;76:97–100.
11.
Kara A, Kanra G, Alanay Y: Localized acquired hypertrichosis following cast application. Pediatr Dermatol 2001;18:57–59.
12.
Dawber RPR: Hair science; in Dawber RPR (ed): Hair and Scalp Disorders. London, Taylor & Francis, 2005, pp 1–37.
13.
Tobin DJ: Gerontobiology of the hair follicle; in Trüeb RM, Tobin DJ (eds): Aging Hair. Berlin, Springer, 2010, pp 1–8.
14.
Courtois M, Loussouarn G, Hourseau C, Grollier JF: Ageing and hair cycles. Br J Dermatol 1995;132:86–93.
15.
Rebora A, Guarrera M: Kenogen: a new phase of the hair cycle? Dermatology 2002;205:108–110.
16.
Sänger CF, Dietrich N, Pelivani N, Borradori L, de Viragh PA: Hairy pinnae after orchiectomy and chemotherapy for testicular cancer: acquired localized hypertrichosis of the ears. Dermatology 2011;222:289–291.
Copyright / Drug Dosage / Disclaimer
Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher.
Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.
You do not currently have access to this content.