Dermatofibroma (DF) is a common benign fibrohistiocytic lesion which presents with a wide variety of clinicopathological features. Generally, the clinical diagnosis is easy, but differentiating it from other cutaneous tumors could be difficult in atypical cases and rare variants. We may find at least four different histopathological variants of DF; more than one of which may be present in a single tumor. Hemosiderotic DF is a variant composed of numerous small vessels, extravasated erythrocytes, and intra- and extracellular hemosiderotic deposits. The differential diagnosis may comprise melanoma as well as other melanocytic and nonmelanocytic tumors. We report the case of a 38-year-old man who presented with a hemosiderotic DF on the abdomen.

1.
From L, Assaad D: Neoplasms, pseudoneoplasms, and hyperplasias of the dermis; in Freedberg IM, Eisen AZ, Wolf K, Austen KF, Goldsmith LA, Katz SI, Fitzpatrick TB (eds): Fitzpatrick’s Dermatology in General Medicine, ed 5. New York, McGraw-Hill, 1999, vol 1, pp 1168–1169.
2.
Ferrari A, Soyer HP, Peris K, Argenziano G, Mazzocchetti G, Piccolo D, De Giorgi V, Chimenti S: Central white scarlike patch: a dermoscopic clue for the diagnosis of dermatofibroma. J Am Acad Dermatol 2000;43:1123–1125.
3.
Argenziano G, Soyer HP, Chimenti S, et al: Dermoscopy of pigmented skin lesions: results of a consensus meeting via the Internet. J Am Acad Dermatol 2003;48:679–693.
4.
Hairston MA Jr, Reed RJ: Aneurysmal sclerosing hemangioma of skin. Arch Dermatol 1966;93:439–442.
5.
Unna PG: Histopathologie der Hautkrankheiten. Berlin, Hirschwald, 1894, pp 839–842.
6.
Diss MA: Histiocytome hémosidérinique pseudomélanique de la peau. Bull Soc Fr Dermatol Syphiligr 1938;45:1903–1908.
7.
Zelger BG, Zelger B: Dermatofibroma. Ein klinisch-pathologisches Klassifikationsschema. Pathologe 1998;19:412–419.
8.
Santa Cruz DJ, Kyriakos M: Aneurysmal (‘angiomatoid’) fibrous histiocytoma of the skin. Cancer 1981;47:2053–2061.
9.
Zalaudek I, Argenziano G, Di Stefani A, Ferrara G, Marghoob AA, Hofmann-Wellenhof R, Soyer HP, Braun R, Kerl H: Dermoscopy in general dermatology. Dermatology 2006;212:7–18.
10.
Zaballos P, Llambrich A, Ara M, Olazaran Z, Malvehy J, Puig S: Dermoscopy findings of haemosiderotic and aneurysmal dermatofibroma: report of six patients. Br J Dermatol DOI: 10.1111/j.1365-2133.2005.06844.x
11.
Blum A, Jawovski S, Metzler G, Bauer J: Lessons on dermoscopy: dermoscopic pattern of hemosiderotic dermatofibroma. Dermatol Surg 2004;30:1354–1355.
12.
Carli P, Massi D, de Giorgi V, Giannotti B: Clinically and dermoscopically featureless melanoma: when prevention fails. J Am Acad Dermatol 2002;46:957–959.
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