We describe a 40-year-old male who presented with sarcoidal granulomas not only at the entry site of an industrial lubricating oil containing silicone in the right thumb, but also in a regional lymph node and at the entry points of venepuncture in both forearms. Laboratory tests and chest X-ray showed no evidence of sarcoidosis.

Keywords:
Sarcoidal granuloma, Silica, Silicone, Industrial oil
1.
Strutton G: The granulomatous reaction pattern; in Weedon D (ed): The Skin, ed 3. Edinburgh, Churchill Livingstone, 1992, vol 9, pp 181–208.
2.
Caputo V, Fiorella S: Sea urchin granuloma. Dermatology 2005;210:254–256.
3.
Pimental L, Barnadas M, Vidal D, Sancho F, Fontarnau R, Alomar A: Simultaneous presentation of silicone and silica granuloma: a case report. Dermatology 2002;205:162–165.
4.
Yanagihara M, Fujii T, Wakamatu N, Ishizaki H, Takehara T, Nawate K: Silicone granuloma on the entry points of acupuncture, venepuncture and surgical needles. J Cutan Pathol 2000;27:301–305.
5.
Walsh NMG, Hanly JG, Termaine R, Murray S: Cutaneous sarcoidosis in foreign bodies. Am J Dermatopathol 1993;15:203–207.
6.
Payne CM, Thomas RH, Black MM: From silica granuloma to scar sarcoidosis. Clin Exp Dermatol 1983;8:171–175.
7.
Gaber Y: Secondary lymphoedema of the lower leg as an unusual side-effect of a liquid silicone injection in the hips and buttocks. Dermatology 2004;208:342–344.
8.
Narini PP, Semple JL, Hay JB: Repeated exposure to silicone gel can induce delayed hypersensitivity. Plast Reconstr Surg 1995;96:371–380.
9.
Naoum C, Dasiou-Plakida D, Pantelidaki K, Dara C, Chrisanthakis DD, Perissios A: A histological and immunohistochemical study of medical-grade fluid silicone. Dermatol Surg 1998;24:867–870.
10.
Leong AS: Pathologic findings in silicone spallation: Autopsy and biopsy studies. Ann Acad Med Singapore 1983;12:304–310.
11.
Bourbigot B, Buzelin F, Fontenaille C, Dubigeon P, Mussini-Montpellier J: Silicone deposits in macrophages of patients on chronic hemodialysis. Nephrologie 1983;4:123–128.
12.
Burgdorf WHC, Hoxtell EO, Bart BJ: Sarcoid granulomas in venipuncture site. Cutis 1979;24:52–53.
13.
Rafnsson V, Ingimarsson O, Hjalmarsson I, Gunnarsdottir H: Association between exposure to crystalline silica and risk of sarcoidosis. Occup Environ Med 1998;55:657–660.
© 2006 S. Karger AG, Basel
2006
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