Background: There are few objective descriptions of the age-related changes taking place on the lips and perioral skin. This zone, however, has great importance in relational functions. Objectives: To describe quantitatively the age-related changes in dimension of the lips and the appearance of the perioral wrinkles, to revisit, thanks to a new method, the pattern of the lip furrows, to compare the hydration states of the upper and lower lips. Methods: On 100 women, we clinically scored wrinkles, dryness of the lips and the general photoageing of the facial skin. We used a Corneometer® for measuring dryness of the lips and SkinChip® for recording lip surface patterns. Results: The upper lip is more hydrated than the lower one, and there is no correlation between lip capacitance and the clinical score of lip dryness. The surface pattern can be classified into 3 main groups with no relation to age. Wrinkle number and visibility are linearly related to age, becoming visible during the fifth decade. The intercommissural distance increases with age, whereas lip height decreases.Conclusions: Both lips are different in terms of dryness. Inversely to their surface pattern, their dimensions are markedly changed with age. The time of apparition of vertical wrinkles suggests a possible influence of hormones.

1.
Lanfranchi HE, de Rey BM: Comparative morphometric analysis of vermillion border epithelium and lip epidermis. Acta Anat 1978;101:187–191.
2.
Hashimoto K: Fine structure of horny cells of the vermillion border of the lip compared with skin. Arch Oral Biol 1971;16:397–406.
3.
Nagase K, Ando Y, Hirose O, et al: Characters and age-associated changes on lip surface. J Soc Cosmet Chem Jpn 1991;25:21–26.
4.
Maruyama M, Sugamuma M, Tuchiya C, et al: Research on the seasonal change of lip surface condition. J Soc Cosmet Chem Jpn 1989;23:183–189.
5.
Fauvel Y, Levilain M, Fontaine G: Etudes des empreintes labiales par une méthode au silicium organique. LARC Med 1982;6:465–471.
6.
Hirth L, Gottsche H, Goedde HW: Lip prints: Variability and genetics. J Hum Evol 1977;6:709–710.
7.
Suzuki K, Tsushihashi Y: Personal identification by means of lip prints. J Forens Med 1970;17:88–102.
8.
Guerrissi JO: Surgical treatment of the senile upper lip. Plast Reconstr Surg 2000;106:938–940.
9.
Aiache AE: Rejuvenation of the perioral area. Dermatol Clin 1997;15:665–672.
10.
Lévêque JL, Querleux B: SkinChip, a new tool for investigating the skin surface in vivo. Skin Res Technol 2003;9:343–347.
11.
Kajiwara R, Okada Y, Matsunaga K, Ueda H: Lip chapping: Clinical findings and parameters. J Soc Cosmet Chem Jpn 1994;18:133–138.
12.
Lévêque JL: EEMCO guidance for the assessment of skin topography. J Eur Acad Dermatol Venereol 1999;12:103–114.
13.
Fogel ML, Stranc MF: Lip function: A study of normal lip parameters. Br J Plast Surg 1984;37:542–549.
14.
Lévêque JL, Grove G, de Rigal J, et al: Biophysical characterization of dry facial skin J Soc Cosmet Chem 1987;82:171–177.
15.
Dong JK, Jin TH, Oh SC: The esthetics of the smile: A review of some recent studies. Int J Prosthodont 1999;12:9–19.
16.
Guerrissi JO, Sanchez LI: An approach to the senile upper lip. Plast Reconstr Surg 1993;92:1187–1191.
17.
Akgul AA, Toygar TU: Natural craniofacial changes in the third decade of life: A longitudinal study. Am J Orthod Dentofac Orthop 2002;122:512–522.
18.
Denes Z: Lips and labial regions in old age. ZFA 1982;37:281–286.
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