Myoepithelioma originates almost exclusively from myoepithelial cells of the salivary, prostate and mammary glands. The skin is a very rare site where myoepithelioma occurs. We describe a patient with a myoepithelioma on the right cheek seen as a subcutaneous nodule that was separated from the parotid gland at surgical resection. Histopathological findings were consistent with those of a myoepithelioma that had originated from the parotid gland, suggesting that this tumor may have developed from the accessory parotid gland.

Sciubba JJ, Brannon RB: Myoepithelioma of salivary glands: Report of 23 cases. Cancer 1982;49:562–572.
Kutzner H, Mentzel T, Kaddu S, Soares LM, Sangueza OP, Requena L: Cutaneous myoepithelioma: An under-recognized cutaneous neoplasm composed of myoepithelial cells. Am J Surg Pathol 2001;25:348–355.
Kilpatrick SE, Hitchcock MG, Kraus MD, Calonje E, Fletcher CDM: Mixed tumors and myoepitheliomas of soft tissue: A clinicopathologic study of 19 cases with a unifying concept. Am J Surg Pathol 1997;21:13–22.
Gugliotta P, Sapino A, Macrí L, Skalli O, Gabbiani G, Bussolati G: Specific demonstration of myoepithelial cells by anti-alpha smooth muscle actin antibody. J Histochem Cytochem 1988;36:659–663.
Morinaga S, Nakajima T, Shimosato Y: Normal and neoplastic myoepithelial cells in salivary glands: An immunohistochemical study. Hum Pathol 1987;18:1218–1226.
Singh R, Cawson RA: Malignant myoepithelial carcinoma (myoepithelioma) arising in a pleomorphic adenoma of the parotid gland: An immunohistochemical study and review of the literature. Oral Surg Oral Med Oral Pathol 1988;66:65–70.
Eckert F, Betke M, Schmoeckel C, Neuweiler J, Schmid U: Myoepithelial differentiation in benign sweat gland tumors demonstrated by a monoclonal antibody to alpha-smooth muscle actin. J Cutan Pathol 1992;19:294–301.
Erlandson RA, Cardon-Cardo C, Higgins PJ: Histogenesis of benign pleomorphic adenoma (mixed tumor) of the major salivary glands: An ultrastructural and immunohistochemical study. Am J Surg Pathol 1984;8:803–820.
Dardick I, Thomas MJ, van Nostrand AWP: Myoepithelioma – New concepts of histology and classification: A light and electron microscopic study. Ultrastruct Pathol 1989;13:187–224.
Barnes L, Appel BN, Perez H, El-Attar AM: Myoepitheliomas of the head and neck: Case report and review. J Surg Oncol 1985;28:21–28.
Dardick I, van Nostrand AWP: Morphogenesis of salivary gland tumors: A prerequisite to improving classification. Pathol Annu 1987;22:1–53.
Saku T, Syuu S: Myoepithelioma (in Japanese). Byouri to Rinshou 1999;17:824–825.
Grossniklaus HE, Wojno TH, Wilson MW, Someren AO: Myoepithelioma of the lacrimal gland. Arch Ophthalmol 1997;115:1588–1590.
Bégin LR, Rochon L, Frenkiel S: Spindle cell myoepithelioma of the nasal cavity. Am J Surg Pathol 1991;15:184–190.
Martínez-Mardigal F, Payán HS, Meneses A, Malagón D, Rojas ME: Plasmacytoid myoepithelioma of the laryngeal region: A case report. Hum Pathol 1995;26:802–804.
Fernándes-Figueras M, Puig L, Trias I, Lorenzo J, Navas-Palacios J: Benign myoepithelioma of the skin. Am J Dermatopathol 1998;20:208–212.
Perzik SL, White IL: Surgical management of preauricular tumors. Am J Surg 1966;112:498–503.
Kawashima Y, Kobayashi D, Ishikawa N, Kishimoto S: A case of myoepithelioma arising in an accessory parotid gland. J Laryngol Otol 2002;116:474–476.
Copyright / Drug Dosage / Disclaimer
Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher.
Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.
You do not currently have access to this content.