Some of the views presented in the chapter on ‘Examination of stratum corneum hydration state by electrical methods’ in Skin Bioengineering – Techniques and Applications in Dermatology and Cosmetology (Karger, 1998) are in strong disagreement with the results from basic research that has been conducted on skin impedance measurement over the last decades. This research has e.g. non-ambiguously shown that the frequency response of the stratum corneum does not obey the Cole equation and that measurement depth is strongly dependent on measurement frequency. One consequence of these findings is that multifrequency electrical measurements on stratum corneum are impossible to achieve in vivo with any electrode system known today. Hence, electrical measurements of stratum corneum hydration must be conducted at one single, low frequency.

Elsner P, Barel AO, Berardesca E, Gabard B, Serup J (eds): Skin Bioengineering: Techniques and Applications in Dermatology and Cosmetology. Basel, Karger, 1998.
Yamamoto T, Yamamoto Y: Electrical properties of the epidermal stratum corneum. Med Biol Eng 1976;14:151–158.
Martinsen ØG, Grimnes S, Sveen O: Dielectric properties of some keratinized tissues. 1. Stratum corneum and nail in situ. Med Biol Eng Comput 1997;35:172–176.
Clar EJ, Her CP, Sturelle CG: Skin impedance and moisturization. J Soc Cosmet 1975;26:337–353.
Leveque JL, De Rigal J: Impedance methods for studying skin moisturization. J Soc Cosmet Chem 1983;34:419–428.
Ollmar S, Nicander I: Information in multi-frequency measurement on intact skin. Innov Tech Biol Med 1995;16:745–751.
Martinsen ØG, Grimnes S, Karlsen J: Electrical methods for skin moisture assessment. Skin Pharmacol 1995;8:237–245.
Martinsen ØG, Grimnes S, Haug E: Measuring depth depends on frequency in electrical skin impedance measurements. Skin Res Technol 1999;5:179–181.
Foster KR, Schwan HP: Dielectric properties of tissues and biological materials: A critical review. Crit Rev Biomed Eng 1989;17:25–104.
Tagami H: Hardware and measuring principle: Skin conductance; in Elsner P, Berardesca E, Maibach HI (eds): Bioengineering of the Skin: Water and the Stratum corneum. Boca Raton, CRC Press, 1994, pp 197–203.
Courage W: Hardware and measuring principle: Corneometer; in Elsner P, Berardesca E, Maibach HI (eds): Bioengineering of the Skin: Water and the Stratum corneum. Boca Raton, CRC Press, 1994, pp 171–175.
Grimnes S, Martinsen ØG, Mørk C: Can skin hydration be estimated from electrical measurements? Skin Res Technol 1996;2:213.
Martinsen ØG, Grimnes S, Henriksen I, Karlsen J: Measurement of the effect of topical liposome preparations by low frequency electrical susceptance. Innov Tech Biol Med 1996;17:217–222.
Martinsen ØG, Grimnes S, Kongshaug ES: Dielectric properties of some keratinized tissues. 2. Human hair. Med Biol Eng Comput 1997;35:177–180.
Martinsen ØG, Grimnes S, Karlsen J: Low frequency dielectric dispersion of microporous membranes in electrolyte solution. J Coll Interface Sci 1998;199:107–110.
Martinsen ØG, Grimnes S: On using single frequency electrical measurements for skin hydration assessment. Innov Tech Biol Med 1998;19:395–399.
Martinsen ØG, Grimnes S, Nilsen SH: New measuring cells for absolute water content and electrical admittance of keratinised tissues. Med Biol Eng Comput 1997;35(suppl):348.
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