Dermatofibrosarcoma protuberans is not a difficult tumor to recognize because of its characteristic clinical appearance, although some unusual variants have been reported. We describe the atrophic variant of dermatofibrosarcoma protuberans in a 21-year-old female. The lesion was a smooth-surfaced, oval depression on the left subclavicular area, with a violaceous plaque at the center. The suspected clinical diagnosis did not include fibrous tumors, although histological examination showed the typical picture of dermatofibrosarcoma protuberans. Positive CD34 staining was also helpful in the diagnosis. We review 14 cases of the atrophic variant of dermatofibrosarcoma protuberans in the literature. Dermatologists should be aware of this uncommon but characteristic appearance of atrophic dermatofibrosarcoma protuberans.

1.
Gloster HM Jr: Dermatofibrosarcoma protuberans. J Am Acad Dermatol 1996;35: 255–274.
2.
Lambert WC, Abbamovits W, Gonzalez-Sevra A, Souchon E, Schwartz RA, Little WP Jr: Dermatofibrosarcoma non-protuberans: Description and report of five cases of a morphea form variant of dermatofibrosarcoma. J Surg Oncol 1985;28:7–11.
3.
Ashack RJ, Tejada E, Parker C, Hanke CW: A localized atrophic plaque on the back: Dermatofibrosarcoma protuberans (atrophic variant). Arch Dermatol 1990;128:1549–1551.
4.
Bednar B: Storiform neurofibromas of the skin, pigmented and nonpigmented. Cancer 1957; 10:367–376.
5.
Frierson HF, Cooper PH: Myxoid variant of dermatofibrosarcoma protuberans. Am J Surg Pathol 1983;7:445.
6.
Banerjee SS, Haris M, Eyden BP, Hamid BNA: Granular cell variant of dermatofibrosarcoma protuberans. Histopathology 1990;17:375.
7.
Page EH, Assaad DM: Atrophic dermatofibroma and dermatofibrosarcoma protuberans. J Am Acad Dermatol 1987;17:947–950.
8.
Sei Y, Kimura A, Kobayashi H, Ishikura N, Yasuda Y: Dermatofibrosarcoma protuberans representing a depressed lesion (in Japanese). Skin Res 1986;28:638–643.
9.
Zelger BW, Ofner D, Zelger BG: Atrophic variant of dermatofibroma and dermatofibrosarcoma protuberans. Histopathology 1995; 26:519–527.
10.
Chuan MT, Tsai TF, Wu MC, Wong TH: Atrophic pigmented dermatofibrosarcoma presenting as infraorbital hyperpigmentation. Dermatology 1997;194:65–67.
11.
Kobayashi T, Hasegawa Y, Konohana A, Nakayama N: A case of Bednar Tumor: Immunohistochemical positivity for CD34. Dermatology 1997;195:57–59.
12.
Kamino H, Jacobson M: Dermatofibroma extending into the subcutaneous tissue. Am J Surg Pathol 1990;14:1156–1164.
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