Background: Though rarely reported, mucin deposition may be observed in scleroderma. Objective: To verify the frequency of significant amounts of mucin in the biopsy specimens. Methods: Biopsies from 20 patients with scleroderma were reviewed and stained to verify the presence of mucin. Results: Mucin deposits were found in all of the 20 specimens. Conclusion: Mucin deposition is probably a constant feature in both morphea and systemic scleroderma. Its relevance in differential diagnosis between scleredema and scleroderma is debatable.

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