The efficacy and tolerability of a novel stiff dithranol stick (Ditrastick®, Orion, Espoo, Finland) were evaluated in an open multicenter trial comprising 121 outpatients with limited psoriasis of the plaque type. Daily treatment was startet with 1.5% dithranol sticks and continued in most patients with 3% sticks after 2 weeks. An excellent or good result was obtained in over half of the patients. Early irritation of a rather narrow rim of the skin surrounding the lesions was common, but only about 10% of the patients discontinued the trial due to this side effect. Paraffin-based dithranol sticks thus enable ambulatory treatment of chronic plaque psoriasis in the areas of predilection. Dithranol is stable in this novel preparation for at least 3 years.

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