... concentration was 564 ± 114 plEq/ml in the fetus compared to 656 ± 70 plEq/ml in the mother. The serum PTH concentration was higher in 2 and lower in 3 fetuses than the Table I. Gestational age and maternal and fetal serum PTH levels Sheep Gestational age days Serum PTH concentration plEq/ml fetal maternal 160...

... mal Research. Arterial Segment Preparation The ewe and fetus(es) were euthanized with so­ dium pentobarbital (50 mg/kg) given intravenously to the ewe, and the fetuses were delivered by cesarean sec­ tion. The fetal lungs and the mesentery containing the cephalic mesenteric arterial cascade were...

... cocaine concentration in the ewe (r = 0.52, p < 0.01) and in the fetus (r = 0.43, p =0.05). In addition, in 7 of 8 fetuses which had entered rapid eye movement (REM) sleep within 5 min of maternal cocaine administration, REM sleep was abruptly terminated either by the cocaine, fetal hypoxia or some...

... has been reported [6], In addi­ tion, acetaminophen overdosage and intoxi­ cation have been frequently reported in in­ fants and children [7-13], Investigation on the disposition of acetaminophen in preg­ nant animals and their fetuses and in neona­ tal animals is therefore essential to assess...

... preparation used in these studies [4; Burchfield et al., in press]. Briefly, pregnant ewes at 125 days gestation (145 days equals term) carrying singleton fetuses were anesthetized with halothane, and a midline abdominal incision was made for expo­ sure of the fetus. Polyvinyl catheters were implanted in both...

... Material Human fetuses were obtained at legal abortions which were performed on sociomedical indications. Fetal age ranged from 14 to 27 weeks. The liver was obtained within 20 min from abortion and stored at - 80 ° C. The consent for this study was obtained from the ethical committee of the Uppsala...

... resec­ tion of the organ. All tissue specimens included in the study had normal cell structure and were stored at -80°C. Specimens of human fetal liver, adrenals, kidney, lung and gut were obtained at legal abortion per­ formed on sociomedical indication from 6 fetuses whose ages ranged between 18 and 25...

... of Neuroregulators during Development: Monoamines and Neuropeptides Key Words Neuroregulators Fetus Infant Adrenal medulla Respiratory control Abstract The turnover of catecholamines (CA) was determined in the adrenal medulla and brain of rat fetuses and pups. In general we found a considerable increase soon after...

... in the early newborn seems to be independent of the gestational age at birth (between 25 and 35 weeks) suggesting that birth is a major determinant of CYP2D6 expression (fig. 2b). CYP2D6 content in the fetus was further investigated in relation to gestational age and cause of absorption. Indeed, 47% of fetuses...

... teratogens have been identified whereas a large number of compounds have not been documented to im­ pose fetal risk when used as recommended [1], Even the most potent human teratogens, such as retinoids and thalidomide, adversely affect only some fetuses while sparing many others. This variability...

... before usc. Clinical data on thc mothers of the fetuses and the adult patien ts are given in table I. The projcct was approved by the Ethical Cornmittee of the Huddinge University Hospital and by thc Swedish National Board of Health and Welfare. Thc liver and kidney samples were homogenizcd in 0.25 M...

... + ratios were higher than (U/P)iothalamate ratios in 7 out of 19 fetuses over 125 days and in 1 fetus between 101 and 125 days, indicating frank secretion of potassium by the fetal tubular cells. Similar findings have also been described previously by Merlet-Benichou and de Rouffignac (20) in near-term...

... effects which were significantly higher with fetal than with adult albumin. 19 2 2019 Furosemide Binding Albumin Fetus Adult man Dev Pharmacol Ther 1991;16:33-40 1617219 © 1991 S. Karger AG, Basel 0379-8305/91/0161-0033S2 75/0 Binding of Furosemide to Albumin Isolated from Human Fetal...

... or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Fetus EGF Receptors Lung Brain Thyroid 1610755 Dev. Pharmacol...

..., St. Louis) and drink water ad libitum. For fetal studies, the does were sacrificied at 22, 27, 28 and 30 days of gestation (0 = day of breeding, term ~ 31 days) by intravenous pentobarbitone after collecting blood from the marginal ear vein. Fetuses were delivered after hysterotomy and killed...

...Jahangir Ayromlooi Maternal and fetal responses to i.v. admission of propranolol (4 mg/4 min) were investigated in 10 ‘steady-state’ sheep experiments performed on 5 ewes and their fetuses at 101-128 days of gestation. Observations were made at 0, 5, 15, 30,45, 60, 75, 90 and 120 min from the start...

..., instructions or products referred to in the content or advertisements. Diazepam Salicylic acid Digitoxin Binding Albumin Fetus Adult Humans Dev Pharmacol Ther 1991;17:100-108 1611056 © 1991 S. Karger AG, Basel 0379-8305/91/0172-0100Î2.75/0 Binding of Diazepam, Salicylic Acid and Digitoxin...

... Carlo Erba (Milan, Italy). Biological Materials Specimens of human fetal liver, lungs, kidneys, gut and placenta were obtained at legal abortions per­ formed on sociomedical indications. The age of the fetuses ranged between 15 and 25 weeks. Wedge adult liver specimens were obtained from patients...

..., gut and placenta were obtained at legal abortions per­ formed on sociomedical indication. The age of the fetuses ranged between 14 and 27 weeks. Wedge liver specimens were obtained from adult patients of either sex (age between 28 and 75 years) subjected to laparotomy for cholecystectomy. Liver...

... (fig. 1). Disappearance of 3H-l,25-(OH)2-D3 in all fetuses (n = 5) and ewes (n = 4) was curvilinear (fig. 2, 3). Initial disappearance of 3H-l,25-(OH)2-D3 from the fetus to the ewe across the placenta was noted in four experiments. Transfer of 3H-l,25-(OH)2-D3 to the mother was noticed within 5-10 min...