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Keywords: Children
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Journal Articles
Subject Area:
Pharmacology
Developmental Pharmacology and Therapeutics (1980) 1 (5): 265–273.
Published Online: 19 February 2019
...Dennis Gurwitz; Henry Levison To assess the dose of oral fenoterol, a ß2-receptor stimulant, which provided optimal bronchodilation with minimal side effects, we studied 12 children using a doubleblind crossover comparison of three dose levels, 2.5, 5 and 7.5 mg, and a placebo. Ventilatory function...
Journal Articles
Subject Area:
Pharmacology
Developmental Pharmacology and Therapeutics (1990) 14 (3): 141–147.
Published Online: 19 February 2019
...Vasundhara Tolia; Sandra L. Fleming; Ralph E. Kauffman We performed a prospective, randomized, double-blind study of 41 children(6-18 years of age) who were undergoing esophagogastroduodenoscopy (EGD) to compare the efficacy of diazepam and midazolam with respect to quality of sedation and amnesia...
Journal Articles
Subject Area:
Pharmacology
Developmental Pharmacology and Therapeutics (1991) 17 (3-4): 180–186.
Published Online: 11 August 2017
...Shinya Ito; Ryuuji Oka; Akira Tsuchida; Hajime Yoshioka We described the pharmacokinetics of acetylsalicylic acid and salicylic acid in 5 children with prior Kawasaki disease receiving buffered aspirin tablets or intravenous aspirin DL-lysine. Oral aspirin is characterized by its longer mean...
Journal Articles
Journal Articles
Subject Area:
Pharmacology
Developmental Pharmacology and Therapeutics (1984) 7 (Suppl. 1): 206–212.
Published Online: 11 August 2017
...E. Rey; M. Nandakumaran; M.O. Richard; J.P. Loose; P. d’Athis; C. Saint-Maurice; G. Olive Flunitrazepam Pharmacokinetics Rectal administration Children 1984 Copyright / Drug Dosage / Disclaimer Copyright: All rights reserved. No part of this publication may be translated into other...
Journal Articles
Subject Area:
Pharmacology
Developmental Pharmacology and Therapeutics (1989) 13 (1): 11–20.
Published Online: 11 August 2017
...C. Hultquist; C. Lindberg; L. Nyberg; B. Kjellman; G. Wettrell Seven asthmatic children were given terbutaline intravenously. The intact drug was measured in plasma and urine, and its conjugates were measured in urine. The decreasing plasma concentrations of terbutaline did not attain a terminal...
Journal Articles
Journal Articles
Subject Area:
Pharmacology
Developmental Pharmacology and Therapeutics (1981) 3 (2): 74–82.
Published Online: 11 August 2017
... weeks) to study the behavioral,autonomic and side effects of caffeine. Mothers of the whole sample and children who were low caffeine users could distinguish between drug conditions by side effects. Caffeine increased autonomic reactivity of low users only. Behavioral and autonomic results were...
Journal Articles
Subject Area:
Pharmacology
Developmental Pharmacology and Therapeutics (1984) 7 (4): 221–228.
Published Online: 11 August 2017
... Shwachman score. 11 8 2017 1610789 Dev. Pharmacol. Then 7; 221-228 (1984) Cephalexin Pharmacokinetics in Patients with Cystic Fibrosis 1 Milap C. Nahata, A. Harold Lubin, James A. Visconti Colleges of Pharmacy and Medicine, Ohio State University and Children s Hospital, Columbus, Ohio, USA Key...
Journal Articles
Journal Articles
Subject Area:
Pharmacology
Developmental Pharmacology and Therapeutics (1986) 9 (3): 145–170.
Published Online: 11 August 2017
... Prednisone L-Asparaginase Cyclophosphamide Methotrexate 6-mercaptopurine Pharmacology Cytosine arabinoside Children 1986 Copyright / Drug Dosage / Disclaimer Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form...
Journal Articles
Subject Area:
Pharmacology
Developmental Pharmacology and Therapeutics (1991) 17 (1-2): 79–87.
Published Online: 11 August 2017
...-concentration relationships indicate that children, especially those under 11 years of age, may require maintenance PB doses more than 5 mg/kg/day to achieve the commonly recommended 'therapeutic' concentration range (10-40 mg/l). 1991 Copyright / Drug Dosage / Disclaimer Copyright: All rights reserved...
Journal Articles
Subject Area:
Pharmacology
Developmental Pharmacology and Therapeutics (1982) 4 (1-2): 12–17.
Published Online: 11 August 2017
...Tsujimoto Aiko; Gozho Tsujimoto; Takashi Ishizaki; Shimpei Nakazawa; Ichihashi Yasuo In 2 children who accidentally received haloperidol (0.26 mg/kg in one and 0.10 mg/kg in another) from a prescription error, haloperidol concentrations in serum in both cases and in cerebrospinal fluid in one case...
Journal Articles
Subject Area:
Pharmacology
Developmental Pharmacology and Therapeutics (1986) 9 (4): 231–240.
Published Online: 11 August 2017
...Laura L. Norling; David Goldring; Antonio Hernandez; Alan M. Robson; Michael Landt We have investigated the sodium-lithium countertransport system as a screening test for hypertensive disease in children and adolescents using the method of Canessa et al. [New Engl. J. Med. 302: 772-776, 1980...
Journal Articles
Subject Area:
Pharmacology
Developmental Pharmacology and Therapeutics (1992) 19 (2-3): 99–105.
Published Online: 11 August 2017
...Shinya Ito; Yuuichi Kusunoki; Toshiaki Oka; Yoshiya Ito; Akimasa Okuno; Hajime Yoshioka Disposition of méthylprednisolone was characterized in 11 children receiving the high-dose therapy (26.0 mg/kg on average). After intravenous infusion, méthylprednisolone hemisuccinate was rapidly converted...
Journal Articles
Subject Area:
Pharmacology
Developmental Pharmacology and Therapeutics (1993) 20 (3-4): 129–134.
Published Online: 11 August 2017
... children. Dose simulations were performed on the basis of individual data of each child in order to obtain steady-state plasma concentrations between 4 and 18 mg/1 permitting the best antipyretic effect for each child. In infants aged less than 10 days a 15 mg/kg dose of propacetamol four times a day (i.e...
Journal Articles
Subject Area:
Pharmacology
Developmental Pharmacology and Therapeutics (1985) 8 (3): 182–188.
Published Online: 11 August 2017
...Milap C. Nahata; Angela W. Miser; James S. Miser; Richard H. Reuning Morphine plasma concentrations were determined in 19 children with cancer. A single dose of morphine, 0.09-0.15 mg/kg, was given intravenously over 3-5 min. The plasma concentrations of morphine ranged from 23 to 472 ng/ml at 10...
Journal Articles
Subject Area:
Pharmacology
Developmental Pharmacology and Therapeutics (1985) 8 (5): 311–328.
Published Online: 11 August 2017
... of microsomal enzymes, competition for renal excretory mechanisms, possible enterohepatic recirculation, binding of drugs to tissues, effects of a drug on another drug’s metabolizing organ, and dose-dependent elimination, on increase or decrease of drug elimination rates in children, have been presented. Based...