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Keywords: Neurodegeneration
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Journal Articles
Dev Neurosci (2025) 47 (2): 139–146.
Published Online: 14 May 2024
... Intrauterine growth restriction Magnetic resonance imaging Neonate Neurodegeneration Placental insufficiency Small for gestational age Fetal growth restriction (FGR) describes a fetus’s inability to attain adequate weight gain based on genetic potential and gestational age and is the second most...
Journal Articles
Journal Articles
Dev Neurosci (2021) 43 (3-4): 222–229.
Published Online: 03 August 2021
... encephalopathies to childhood onset neurodegeneration. Here we review recent evidence demonstrating mitochondrial involvement in neurodevelopmental disorders, identify emerging mechanistic trends, and reconsider the long-standing question of the role of mitochondria in light of new evidence: causation versus mere...
Journal Articles
Journal Articles
Journal Articles
Dev Neurosci (2013) 35 (2-3): 255–264.
Published Online: 27 February 2013
... acetylcholine as the key endogenous mediator. In this study, we investigated the effects of the cholinergic agonists, physostigmine and donepezil, on neurodegeneration, inflammation and oxidative stress during oxygen toxicity in the developing rat brain. The aim of this study was to investigate the level...
Journal Articles
Dev Neurosci (2012) 34 (2-3): 129–139.
Published Online: 08 May 2012
... with neurodegeneration, including high levels of protein degradation and ubiquitination, caspase 3 activation and organelle autophagy, are essential for neural circuit formation [ 19,20 ]. Consequently, protein markers of these processes are abundantly expressed in development (fig. 1 ). Large numbers of neurons...
Journal Articles
Dev Neurosci (2011) 33 (3-4): 199–209.
Published Online: 15 July 2011
... regeneration. Here, we review data that highlight the dual aspects of microglia with a focus on the developing brain, i.e. as aggressors potentiating damage and as helpers in the recovery process following CNS damage. Microglia Brain Neurodegeneration Neuroprotection Inflammation The exact...
Journal Articles
Journal Articles
Dev Neurosci (2010) 32 (3): 197–207.
Published Online: 10 July 2010
..., we investigated whether MDMA exposure during the period of rapid brain growth causes neurodegeneration in the developing rat brain. MDMA significantly enhanced neuronal death in the brains of 6-day-old rat pups at a dose of 60 mg/kg, but no significant toxicity was detected at the ages of 14 and 21...
Journal Articles
Journal Articles
Journal Articles
Dev Neurosci (2005) 27 (2-4): 191–199.
Published Online: 19 July 2005
... group. The depth of hypothermia was associated with increased CA1 hippocampal neuron survival at 5 weeks. Neurodegeneration in the CA1 hippocampus assessed using Fluoro-Jade B labeling at 5 weeks was not detected in the 32°C group, whereas 2/7 and 4/7 rats in the 34 and 37°C groups, respectively, showed...
Journal Articles
Dev Neurosci (2003) 24 (5): 405–410.
Published Online: 21 March 2003
...(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. p38 Mitogen-activated protein kinase Hypoxia-ischemia Neurodegeneration Apoptosis Caspase-3 Neuroprotection...
Journal Articles
Dev Neurosci (2002) 24 (2-3): 114–124.
Published Online: 28 October 2002
... Proteasome Iron regulatory protein 2 (IRP2) Degradation Aging Neurodegeneration Inclusions Heat shock proteins Iron: Oxidative Stress and Neurodegeneration Dev Neurosci 2002;24:114 124 DOI: 10.1159/000065693 Received: March 21, 2002 Accepted: May 3, 2002 Numerous Proteins in Mammalian Cells...
Journal Articles
Dev Neurosci (2002) 24 (2-3): 188–196.
Published Online: 28 October 2002
...(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Iron Metabolism Gene Mutation Single nucleotide polymorphism Neurodegeneration Iron: Oxidative Stress...
Journal Articles
Dev Neurosci (2002) 23 (6): 432–440.
Published Online: 27 February 2002
... Differentiation or Apoptosis in a Dose-Dependent Fashion: Involvement of the Dopamine Transporter and p53 Shai Porat Arumugam Premkumar Rabi Simantov Department of Molecular Genetics, Weizman Institute of Science, Rehovot, Israel Key Words Neurodegeneration W Parkinson s disease W Programmed cell death W DNA...
Journal Articles
Dev Neurosci (1998) 20 (2-3): 146–153.
Published Online: 30 July 1998
... Neurodegeneration Original Paper Dev Neurosci 1998;20:146 153 Received: December 4, 1997 Accepted: January 10, 1998 Burkhard Poeggeler Arash Rassoulpour Paolo Guidetti Hui-Qiu Wu Robert Schwarcz Maryland Psychiatric Research Center, University of Maryland School of Medicine, Baltimore, Md., USA Dopaminergic...
Journal Articles
Journal Articles
Dev Neurosci (1993) 15 (2): 110–120.
Published Online: 10 February 1994
...(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Excitotoxicity GluR2 Glutamate receptors Han-Wistar rats Neurodegeneration Purkinje cells Original Paper Dev...