... (TGF-β) receptor was used as a therapeutic in a rat model of moderate term HI. Here, we have extended those studies to a mouse preterm pup model of HI. For these studies, postnatal day 7 CD1 mice of both sexes were exposed to 35–40 min of HI. Beginning 3 days later, SB505124, the ALK5 receptor...

...), and then determine the efficacy of EPO treatment in this strain and their wild-type (WT) littermates. Thus, mice overexpressing copper/zinc SOD1 were subjected to HI, modified for the P9 mouse, and recombinant EPO (5 U/g) or vehicle (saline) was administered intraperitoneally 3 times: at 0 h, 24 h, and 5 days...

... indicate exclusion justification: (1) surgery-related death, (2) euthanized due to morbidity, (3) euthanized due to malocclusion and (4) euthanized due to skull fracture at impact. Here, we employed a controlled cortical impactor device to generate a closed-skull impact to the mouse brain...

... or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Fetal alcohol spectrum disorders Mouse Neurodevelopment Gene...

... Fluoxetine Serotonin Exposure, perinatal Pregnancy Development Aggression Anxiety Mouse Behaviour Women of childbearing age are the population at the highest risk of depression [ 1 ]. Selective serotonin reuptake inhibitors (SSRIs) are the medication of choice for the treatment of depression...

... symptoms. How these changes are achieved from immediate to long-term effects, and how they are maintained, is unknown. We have used the C57BL/6J mouse to assess the dynamics of genomic alterations following binge alcohol exposure. Ethanol-exposed fetal (short-term effect) and adult (long-term effect...

... of ASD-relevant phenotypes can now be investigated in rodents, including stereotyped and repetitive behaviors, and deficits in social interaction and communication. In this review, we focus on several prevailing mouse models and discuss how studies have advanced our understanding of synaptic mechanisms...

... and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Mouse Dopamine transporter Knockout mice Striatum Locomotion Anxiety Cognition Memory Development, postnatal...

... to in the content or advertisements. Medial frontal cortex Circadian activity patterns Mouse Phase shift Original Paper Dev Neurosci 2009;31:412 419 DOI: 10.1159/000232559 Received: September 30, 2008 Accepted after revision: January 27, 2009 Published online: August 11, 2009 Neonatal Medial Frontal...

... the developmental expression of ADAR family members or the mechanisms responsible for the specific patterns of editing observed for ADAR substrates. We have examined the spatiotemporal expression patterns for ADAR1 and ADAR2 in mouse forebrain. ADAR1 and ADAR2 are broadly distributed in most regions of the mouse...

...A.G.S. Lumsden; A.M. Davies; H.C. Slavkin; G. Burnstock Trigeminal and dorsal root ganglia were excised from mouse embryos of 10 and 18 days in utero age, respectively, and grown in tissue culture. A quantitative method was used to assess the extent of neurite outgrowth from the explants after 24...

...A.M. Davies; A.G.S. Lumsden; H.C. Slavkin; G. Burnstock Developing trigeminal ganglia have been excised from mouse embryos of 9, 10, 11 and 12 days gestation and grown in tissue culture. A quantitative method was used to assess the effect of nerve growth factor (NGF) and an antiserum to NGF (anti...

... of Zoology. University of Stuttgart-Hohenheim, FRG Key Words. 6-Hydroxydopamine Central noradrenergic neurons Rat Mouse Cortex Development Gangliosides Body weight Abstract. In a comparative study newborn rats and mice received subcutaneous (s.c.) injec­ tions of 6-hydroxydopamine (6-OHDA: 100 mg...

..., instructions or products referred to in the content or advertisements. Hippocampus Cortex GABA Interneurons Six3 Dlx5/6 Cre- loxP HGF/SF MET Mouse Original Paper Dev Neurosci 2007;29:143 158 DOI: 10.1159/000096219 Received: December 23, 2005 Accepted: May 10, 2006 Loss of Embryonic MET...

..., St. Louis, Mo., and c Department of Physiology, The University of Texas Southwestern Medical Center at Dallas, Dallas, Tex., USA Key Words Notch Mouse Conditional knockout Spinal cord Neuronal speci cation Homeodomain Basic helixloop-helix Interneuron Motor neuron Chox10 Lim3...

... 5, 2005 Matrix Metalloproteinases and Their Inhibitors in the Developing Mouse Brain and Spinal Cord: A Reverse Transcription Quantitative Polymerase Chain Reaction Study Reiner Ulrich Ingo Gerhauser Frank Seeliger Wolfgang Baumgärtner Susanne Alldinger Department of Pathology, University...

...., USA Key Words Development Guidance Axon Mouse Rat Neurotrophic factor receptor Trk GDNF Geniculate ganglion Abstract We investigated which neurotrophic factors may contribute to the divergence of two peripheral nerves emanating from the geniculate ganglion. We compared receptor mRNA...

... to in the content or advertisements. Neonatal period Brain injury Mouse Stroke Focal ischemia Photothrombosis 7 11 2004 21 12 2004 19 7 2005 Original Paper Dev Neurosci 2005;27:121 126 DOI: 10.1159/000085983 Received: November 7, 2004 Accepted: December 21, 2004 Induction...

... to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Fibroblast growth factor Subventricular zone Mouse Stem cell Cell cycle, progenitor Olfactory bulb Dev Neurosci 2004;26:181 196 DOI: 10.1159/000082136 Received...

...Pedro Benítez-Diaz; Leticia Miranda-Contreras; Rosa Virginia Mendoza-Briceño; Zulma Peña-Contreras; Ernesto Palacios-Prü This study documents the variation in the amino acid neurotransmitter contents during mouse parietal cortex development, from embryonic day 13 (E13) until young adulthood...