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Keywords: Magnetic resonance spectroscopy
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Journal Articles

A Metabolomics Study of Hypoxia Ischemia during Mouse Brain Development Using Hyperpolarized 13 C

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Further Areas , Neurology and Neuroscience , Women's and Children's Health
Alkisti Mikrogeorgiou, Yiran Chen, Byong Sop Lee, Robert Bok, R. Ann Sheldon, A. James Barkovich, Duan Xu, Donna M. Ferriero
Journal: Developmental Neuroscience
Dev Neurosci (2020) 42 (1): 49–58.
https://doi.org/10.1159/000506982
Published Online: 22 June 2020
...Alkisti Mikrogeorgiou; Yiran Chen; Byong Sop Lee; Robert Bok; R. Ann Sheldon; A. James Barkovich; Duan Xu; Donna M. Ferriero Background: Hyperpolarized 13 C spectroscopic magnetic resonance spectroscopy (MRS) is an advanced imaging tool that may provide important real-time information about brain...
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Journal Articles

Assessing Cerebral Metabolism in the Immature Rodent: From Extracts to Real-Time Assessments

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Further Areas , Neurology and Neuroscience , Women's and Children's Health
Alkisti Mikrogeorgiou, Duan Xu, Donna M. Ferriero, Susan J. Vannucci
Journal: Developmental Neuroscience
Dev Neurosci (2019) 40 (5-6): 463–474.
https://doi.org/10.1159/000496921
Published Online: 16 April 2019
... metabolism. Magnetic resonance spectroscopy (MRS) has enabled the acquisition of a snapshot of the metabolic status of the brain as quantifiable spectra of various intracellular metabolites. Proton ( 1 H) MRS has been used extensively as an experimental and diagnostic tool of HI in the pursuit of markers...
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Journal Articles

Combined Diffusion Tensor and Magnetic Resonance Spectroscopic Imaging Methodology for Automated Regional Brain Analysis: Application in a Normal Pediatric Population

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Further Areas , Neurology and Neuroscience , Women's and Children's Health
Nirmalya Ghosh, Barbara Holshouser, Udo Oyoyo, Stanley Barnes, Karen Tong, Stephen Ashwal
Journal: Developmental Neuroscience
Dev Neurosci (2017) 39 (5): 413–429.
https://doi.org/10.1159/000475545
Published Online: 27 June 2017
... maturation Magnetic resonance spectroscopy Pediatric brain Diffusion tensor imaging Computational analysis National Institutes of Health (NIH) 10.13039/100000002 Diffusion tensor imaging (DTI) and magnetic resonance spectroscopic imaging (MRSI) have proven invaluable in noninvasively...
View articletitled, Combined Diffusion Tensor and Magnetic Resonance Spectroscopic Imaging Methodology for Automated Regional Brain Analysis: Application in a Normal Pediatric Population
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Journal Articles

Dexmedetomidine Combined with Therapeutic Hypothermia Is Associated with Cardiovascular Instability and Neurotoxicity in a Piglet Model of Perinatal Asphyxia

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Further Areas , Neurology and Neuroscience , Women's and Children's Health
Mojgan Ezzati, Go Kawano, Eridan Rocha-Ferreira, Daniel Alonso-Alconada, Jane K. Hassell, Kevin D. Broad, Igor Fierens, Bobbi Fleiss, Alan Bainbridge, David L. Price, Pardis Kaynezhad, Brian Anderson, Mariya Hristova, Ilias Tachtsidis, Xavier Golay, Pierre Gressens, Robert D. Sanders, Nicola J. Robertson
Journal: Developmental Neuroscience
Dev Neurosci (2017) 39 (1-4): 156–170.
https://doi.org/10.1159/000458438
Published Online: 08 April 2017
... outcomes. The aim was to assess whether hypothermia + dexmedetomidine treatment augments neuroprotection compared to routine treatment (hypothermia + fentanyl sedation) in a piglet model of NE using magnetic resonance spectroscopy (MRS) biomarkers, which predict outcomes in babies with NE...
View articletitled, Dexmedetomidine Combined with Therapeutic Hypothermia Is Associated with Cardiovascular Instability and Neurotoxicity in a Piglet Model of Perinatal Asphyxia
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Journal Articles

Advanced Neuroimaging in Children with Nonaccidental Trauma

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Further Areas , Neurology and Neuroscience , Women's and Children's Health
Stephen Ashwal, Nathaniel D. Wycliffe, Barbara A. Holshouser
Journal: Developmental Neuroscience
Dev Neurosci (2011) 32 (5-6): 343–360.
https://doi.org/10.1159/000316801
Published Online: 13 October 2010
... associated with diffuse axonal injury (DAI). Magnetic resonance spectroscopy acquires metabolite information reflecting neuronal integrity and function from multiple brain regions and provides a sensitive, noninvasive assessment of neurochemical alterations that offers early prognostic information regarding...
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Journal Articles

Non-Invasive Methods for Studying Brain Energy Metabolism: What They Show and What It Means

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Subject Area:
Further Areas , Neurology and Neuroscience , Women's and Children's Health
G.J. Kemp
Journal: Developmental Neuroscience
Dev Neurosci (2000) 22 (5-6): 418–428.
https://doi.org/10.1159/000017471
Published Online: 04 December 2000
...G.J. Kemp This review summarises the ways in which magnetic resonance spectroscopy (MRS) and related methods can be used as windows on brain energy metabolism in vivo. 31 P-MRS can measure acute changes in non-oxidative ATP synthesis in transient states, and at steady state reflects the balance...
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Journal Articles

Multinuclear NMR Spectroscopy Studies on NH 4 Cl-Induced Metabolic Alterations and Detoxification Processes in Primary Astrocytes and Glioma Cells

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Further Areas , Neurology and Neuroscience , Women's and Children's Health
Claudia Zwingmann, Annette Brand, Christiane Richter-Landsberg, Dieter Leibfritz
Journal: Developmental Neuroscience
Dev Neurosci (1998) 20 (4-5): 417–426.
https://doi.org/10.1159/000017339
Published Online: 30 October 1998
... Methionine sulfoximine Myo -inositol Magnetic resonance spectroscopy NMR 1998 Copyright / Drug Dosage / Disclaimer Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical...
View articletitled, Multinuclear NMR Spectroscopy Studies on NH 4 Cl-Induced Metabolic Alterations and Detoxification Processes in Primary Astrocytes and Glioma Cells
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