... and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. 2024 Animal models Developing brain Hypoxic-ischemic encephalopathy Perinatal brain injury Reperfusion...

... Quantitative electroencephalography Neonatal encephalopathy Hypoxic-ischemic encephalopathy Neonatal encephalopathy (NE) secondary to hypoxia-ischemia is caused by interruption in cerebral blood flow and oxygen delivery around time of birth and can lead to significant lifelong neurologic morbidity...

...Kengo Onda; Raul Chavez-Valdez; Ernest M. Graham; Allen D. Everett; Frances J. Northington; Kenichi Oishi Neonatal hypoxic-ischemic encephalopathy (HIE) is the leading cause of acquired neonatal brain injury with the risk of developing serious neurological sequelae and death. An accurate and robust...

... Progesterone Neuroprotection Hypoxia-ischemia Hypoxic-ischemic encephalopathy Neonatal brain injury Perinatal brain injury Brain injury Despite significant advancement in the field of neonatology, hypoxic-ischaemic encephalopathy (HIE) remains one of the major contributors to early neonatal...

...Ammee A.D. Gala; Himanshu Kumar; Sagar Sedani; Nicola Openshaw-Lawrence; Jan Martin Verkuijl; Nicola Glogowski; Adam Steingold; Vennila Ponnusamy; Georgia Ekitzidou; Ping Yip; Isabell Nessel; Adina T. Michael-Titus; Guus Roeselers; Divyen K. Shah Background: Hypoxic-ischemic encephalopathy (HIE...

..., instructions or products referred to in the content or advertisements. Periventricular white matter necrosis Brain injury Cerebral palsy Hypoxic-ischemic encephalopathy Asphyxia Neuroprotection Preterm birth (before 37 weeks gestation) remains the leading cause of childhood death...

... or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Hypoxic-ischemic encephalopathy Pig Neuroprotection Sulforaphane...

...Eric M. Chin; Srishti Jayakumar; Ezequiel Ramos; Gwendolyn Gerner; Bruno P. Soares; Elizabeth Cristofalo; Mary Leppert; Marilee Allen; Charla Parkinson; Michael Johnston; Frances Northington; Vera Joanna Burton Early studies following perinatal hypoxic-ischemic encephalopathy (HIE) suggested...

...Caitlin E. O’Brien; Polan T. Santos; Ewa Kulikowicz; Michael Reyes; Raymond C. Koehler; Lee J. Martin; Jennifer K. Lee Therapeutic hypothermia is the standard of clinical care for moderate neonatal hypoxic-ischemic encephalopathy. We investigated the independent and interactive effects of hypoxia...

...Melanie A. McNally; Raul Chavez-Valdez; Ryan J. Felling; Debra L. Flock; Frances J. Northington; Carl E. Stafstrom Hypoxic-ischemic encephalopathy is a common neonatal brain injury associated with significant morbidity and mortality despite the administration of therapeutic hypothermia (TH...

... ]. Therapeutic hypothermia has been successfully implemented as a neuroprotective strategy in 2010 (National Institute of Clinical Excellence) [ 38 ]; however, in spite of this, 50% of newborns with moderate to severe hypoxic-ischemic encephalopathy (HIE) will die or suffer long-term disabilities...

.... Hypoxic-ischemic encephalopathy (HIE) contributes to the burden of CP, but the long-term neuropathological findings of this association remain limited. Methodology: Thirty-four term Macaca nemestrina macaques were included in this long-term neuropathological study: 9 control animals delivered by cesarean...

... hypothermia provides incomplete neuroprotection for neonatal hypoxic-ischemic encephalopathy (HIE). We examined whether hemodynamic goals that support autoregulation are associated with decreased brain injury and whether these relationships are affected by birth asphyxia or vary by anatomic region. Methods...

... to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Mass spectrometry Metabonomics Neonatal encephalopathy Hypoxic-ischemic encephalopathy Diffuse white matter injury Metabolomics Ibotenate Stroke Excitotoxicity...

...Ryan M. McAdams; Ronald J. McPherson; Raj P. Kapur; Sandra E. Juul Worldwide, hypoxic-ischemic encephalopathy (HIE) is a major cause of neonatal mortality and morbidity. To better understand the mechanisms contributing to brain injury and improve outcomes in neonates with HIE, better preclinical...

... cerebral artery occlusion. Although neonatal stroke and hypoxic-ischemic encephalopathy (HIE) are grouped under the term “neonatal encephalopathy,” their pathogenesis differs. However, little is known about the differences in the effects of the same treatment between these 2 diseases. In this study, we...

...Monica E. Lemmon; Matthias W. Wagner; Thangamadhan Bosemani; Kathryn A. Carson; Frances J. Northington; Thierry A.G.M. Huisman; Andrea Poretti Background: Despite the benefits of whole-body hypothermia therapy, many infants with hypoxic-ischemic encephalopathy (HIE) die or have significant long...

... hypothermia or to other methodological choices. Close monitoring and control of brain temperature during, as well as for many days after, experimental hypoxia-ischemia are now critical to reliably develop new ways to improve neurodevelopmental outcomes after perinatal hypoxic-ischemic encephalopathy. 27...

... of two-sided tests. Statistical significance was declared for p values <0.05. [email protected] 20 10 2014 16 03 2015 23 5 2015 Cerebral blood flow Hypoxic-ischemic encephalopathy Therapeutic hypothermia Diffuse correlation spectroscopy National...

... cord occlusion (UCO) to induce hypoxic-ischemic encephalopathy and were then delivered by hysterotomy, resuscitated and stabilized. Serial blood samples were obtained at baseline (cord blood) and at 0.1, 24, 48, and 72 h of age. Treatment groups included nonasphyxiated controls (n = 7), untreated UCO...