... or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. 2024 Aging Developing brain Fetal growth restriction Hippocampus...

... and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. 2024 Visual Abstract Valproic acid Autism spectrum disorder Brain volume Hippocampus Anterior cingulate...

... development, however, has been poorly described. The present study aimed to explore miRNA expression in the hippocampus during adolescence compared to adulthood in rats. Method: The brains of female and male Wistar rats were extracted, and the hippocampus was freshly dissected at postnatal day 41 (adolescence...

... in the hippocampus have not yet been sufficiently clarified. Furthermore, it is not known whether dorsal and ventral hippocampi are affected similarly or not in FXS. Method: We used an Fmr1 knockout (KO) rat model of FXS and recordings of evoked field potentials from the CA1 field of transverse slices from both...

... or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. 2023 Subgranuar zone Fluoxetine Neurogenesis Seizures Hippocampus Adult hippocampal neurogenesis (AHN) occurs in the subgranular zone of the dentate gyrus (DG) in most...

...Lauren McClure Yauch; Kathleen Ennis-Czerniak; William H. Frey, II; Ivan Tkac; Raghavendra B. Rao Hyperglycemia due to relative hypoinsulinism is common in extremely preterm infants and is associated with hippocampus-mediated long-term cognitive impairment. In neonatal rats, hypoinsulinemic...

...Sakthi Jothi Muthu; Ganesh Lakshmanan; Khayinmi Wungpam Shimray; Kathiravan Kaliyappan; Sathya Bharathy Sathyanathan; Prakash Seppan The thorny protrusions or spines increase the neuronal surface area, facilitate synaptic interconnections among neurons, and play an essential role in the hippocampus...

..., coverage of capillaries by astrocytic end-feet (AQP4 + ) was significantly reduced. In contrast, there was a significant increase in AQP4 + capillary length in female pups 1 week after LPS injection. GFAP + astrocytes via morphological changes in the hippocampus showed significant enhancement...

...-ischemia Apoptosis Caspase-3 Sirtuin SIRT Brain injury MRI Hippocampus Injury score PARP Nuclei integrity National Institutes of Health (NIH) 10.13039/100000002 The developing brain has been shown to be especially vulnerable to hypoxia-ischemia (HI)-related brain injury...

.... Androgen receptor Hippocampus Learning and memory Neurotrophin Testosterone The clinical and animal model studies have identified several proteins necessary for adult neurogenesis, learning, and memory, and one such family of proteins is neurotrophins (NTs) [1]. NTs are dimeric ligands...

... candidate mechanism because of its dependence on iron-containing TET enzymes. The aim of the present study was to determine the effect of fetal-neonatal ID on regional brain TET activity, Tet expression, and 5hmC in the developing rat hippocampus and cerebellum and to determine whether changes...

...-neutralizing antibody (IL-6Ab) or vehicle during the third week of pregnancy. Newly born (doublecortin) and mature neurons (NeuN) were monitored in the hippocampus of adult male and female offspring. Prenatal IL-6Ab led to an enhanced number of newly born and mature neurons in the dentate gyrus...

... the epigenetic impairment of the perinatal expression of glucocorticoid receptors (GR) in the hippocampus of the progeny, but so far no detailed study of how this affects the functional state of the glucocorticoid system during further ontogenesis has been performed. Objective: The goal of the present study...

...-isoxazolepropionic acid (AMPA), N-methyl-D-aspartate (NMDA) and GABA A receptors in the hippocampus and prefrontal cortex (PFC) of adolescent (P35) and adult (P62) male Wistar rats and their correlations with anxiety-like behavior in adulthood. Methods: The protein levels were assessed by Western blot analysis...

... channel potentiation was performed by one injection of SK2/3 agonist (CyPPA) into the pallium of mice on postnatal day 2 (P2). When the animals reached adulthood (P55), the hippocampus and cortex were examined to assess neuronal maturation, lamination, and the distribution of synaptic cytoskeletal...

... by intra-peritoneal injections of bacterial lipopolysaccharide (LPS) to neonatal rats (two injections of LPS, or saline in the control group, consecutively on postnatal days 3 and 5 [PND3 and PND5]). In females, a significant effect of NPS on hippocampus development was associated with modifications...

... Antibody Cerebral cortex Hippocampus Cerebellum Neuron POGZ (a pogo transposable element-derived protein with zinc finger domain) is a heterochromatin protein 1α-binding protein, which contains a cluster of multiple C2H2-type zinc fingers interacting with proteins or DNAs, a centromere protein...

... functions noted during adolescence [ 12 ]. National Institutes of Health (NIH) 10.13039/100000002 Adolescence Dentate gyrus Hippocampus Neurogenesis Puberty © 2019 S. Karger AG, Basel 2019 Copyright / Drug Dosage / Disclaimer Copyright: All rights reserved. No part...

... processes in the cortical networks. Analyzing protein levels of neurotransmitter transporters in the brain structures of the Hx rats, we found that the content of the glutamate transporter EAAT1 was higher in the parietal cortex in all age groups of Hx rats while in the hippocampus it decreased during...

... were dissociated using a bead-based Precellys homogenizer to generate equivalent homogenates, and levels of protein targets subsequently analyzed by Western blotting. Results: Infants had the highest levels of RBM3 and other CSPs in the brain compared to all other ages. In the hippocampus, CSPs were...