... transfer was rejected. On the other hand, the analysis of glutamate isotopomers from perchloric acid extracts of granule cells incubated with [1- 13 C]glucose indicated that total cycling of oxaloacetate into fumarate occurred in these cells. © 1996 S. Karger AG, Basel 1996 Copyright / Drug Dosage...

... with staining for these markers revealed that the appearance of mossy cells coincided with the first wave of dentate granule cell production during mid-gestation. Since mossy cells are born as the first granule cells are produced and it is believed that mossy cells originate from the neuroepithelium adjacent...

...Shanting Zhao; Xuejun Chai; Michael Frotscher The extracellular matrix protein reelin is essential for the proper radial migration of cortical neurons. In reeler mice lacking reelin, there is a malformation of the radial glial scaffold required for granule cell migration. Immunostaining for glial...

... be recognized in the organotypic hippocampal slice culture preparation generated from p35–/– mouse pups. In these p35–/– cultures, an abnormally high proportion of dentate granule cells migrates into the hilus and molecular layer, and develops aberrant dendritic and axonal morphology. In addition, astrocyte...

... of Jagged1 in the mouse central nervous system, we have inactivated the Jag1 gene in the cerebellar primordium at mid-embryogenesis. Loss of Jagged1 results in aberrant granule cell migration and ectopic differentiation in the external germinal layer and molecular layer of the early postnatal cerebellum. We...

... administering the drug to litters of Long-Evans hooded rats from 18 days postcoitus to 21 days postnatum. Various parameters of Purkinje cell growth were analysed at specific times after treatment utilizing Golgi-prepared specimens. Granule cell density was used as an estimate of parallel fibre numbers. When...