... or supplemented with glutamate and their morphology was compared with in vivo controls of corresponding age. After 15 days in vitro (DIV), E45 retinal explants displayed several signs of atypical development when compared with E60 in vivo controls. First, an accelerated photoreceptor differentiation was evident...

... or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Pten Mammalian target of rapamycin Glutamate Autism Seizure NMDA receptor Epilepsy National Institutes of Health (NIH) 10.13039/100000002 The PTEN...

... pmol/g protein. Up to 79% of.[ 3 H]QNB binding sites were lost within a few days after exposure of the cultures to 1 m M glutamate. This neurotoxic action of glutamate showed a steep concentration dependence in the range 0.1–1 m M and did not vary with the duration of exposure of the cultures from 10...

...N. Brookes The culture of dissociated spinal cord cells of the fetal mouse provides accessibility for electrophysiological analysis of the action of glutamate on these cells. The present study re-evaluates the glutamate reversal potential by means of independent microelectrodes for current...

...Leif Hertz; Elisabeth Bock; Arne Schousboe The effects on GFA content, glutamate uptake and activity of glutamate metabolizing enzymes (glutamine synthetase, glutamate dehydrogenase, glutamate-oxaloacetate transferase) by three variables, i.e., length of culturing period, presence or absence...

... subtypes and glutamate receptor subunits [N-methyl- D -aspartate (NMDAR1) and GluR1] in cortical tissue samples obtained from children (ages 3 months to 16 years) undergoing epilepsy surgery. DA receptor activation produced differential effects depending on the receptor subtype that was activated. D1...

...Niels Westergaard; Ursula Sonnewald; Arne Schousboe Use of 13 C-labeled precursors for the neuroactive amino acids glutamate and GABA as well as [U- 13 C]glutamate and glutamine combined with NMR spectroscopy has allowed detailed studies to be performed on cultured neurons and astrocytes yielding...

...Mary C. McKenna; J. Tyson Tildon; Joseph H. Stevenson; Xueli Huang Studies from several groups have provided evidence that glutamate and glutamine are metabolized in different compartments in astrocytes. In the present study we measured the rates of 14 C0 2 production from U-[ 14 C]glutamate and U...

...-MRS GABA Glia Glutamate Glutamine Glycerol-3-phosphate Neurones Trafficking © 1996 S. Karger AG, Basel 1996 Copyright / Drug Dosage / Disclaimer Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form...

.... The Na + ionophore monensin (10 μ M ) doubled the rate of metabolism, a stimulation that was only partially blocked by ouabain and unaffected by TTX. L -Glutamate (500 μ M ) stimulated [ 14 C]DG phosphorylation in astroglia, but this stimulation was probably secondary to Na + uptake into the cells via...

... receptors and transporters for various neurotransmitters, endowing astrocytes with the capacity to 'sense' synaptic activity. We have previously described the stimulation by L -glutamate of glucose utilization by astrocytes, monitored by 2-deoxyglucose uptake and phosphorylation. Here we have further...

...Richard L. Potter; Albert C. Yu; Arne Schousboe; Leif Hertz The metabolic fate of [U- 14 C]-labeled glutamate in astrocytes grown in primary cultures for 1–3 weeks in the absence or presence of dibutyryl cyclic AMP was followed using dansylation with 3 H-dansyl chloride and subsequent thin layer...

...T. Slevin; M.V. Johnston; K. Biziere; J.T. Coyle Mice whose cerebella were rendered granuloprival by neonatal injection of methylazoxymethanol had decreased cerebellar adult levels of glutamic acid (GA) (–29%), decreased GA presynaptic uptake (–45%) and increased GA postsynaptic binding (+65...

... or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. GABAergic interneurons Cortical development Tangential migration Medial ganglionic eminence AMPA Glutamate Electroporation Original Paper Dev Neurosci 2008;30:105 116 DOI...

..., N.J., USA Key Words Seizures, perinatal Glutamate AMPA receptors Developmental stage Neonate Abstract The effects of single versus multiple episodes of status epilepticus on the expression of AMPA receptors during a critical growth spurt are unknown. To determine whether the pattern...

... neurons Brain slice Brain development Glutamate N-Methyl- D -aspartate receptor MK801 Original Paper Dev Neurosci 2007;29:213 231 DOI: 10.1159/000095221 Received: February 15, 2006 Accepted: April 4, 2006 Published online: August 18, 2006 Widespread Neonatal Brain Damage following Calcium Channel...

...) subclass of glutamate receptors in the proliferation of striatal progenitors. Here, we compare the roles of ionotropic glutamate receptors in the proliferation of either striatal or cortical progenitors. In culture, glutamate receptor activation promoted proliferation of both striatal and cortical...

...Jennifer K. Ness; Nina E. Mitchell; Teresa L. Wood A previous study from our laboratory demonstrated differences in the ability of insulin-like growth factor-I (IGF-I) and neurotrophin-3 (NT-3) to promote survival of pro-oligodendroblasts (pro-OLs) against glutamate-mediated apoptosis...

...Jack E. Turman Jr.; Lauren Hiyama; Marvin Castillo; Scott H. Chandler Trigeminal motoneurons (Mo5), mesencephalic trigeminal neurons (Me5), supratrigeminal neurons (Su5), and intertrigeminal neurons (I5) are important constituents of the neural circuitry responsible for jaw movements. Glutamate...

... glutathione content was reduced by starvation in a minimal medium lacking glucose and amino acids. Resynthesis of glutathione depended on the presence of glucose and the three constituent amino acids glutamate, cysteine and glycine. Absence of glucose reduced the amount of net glutathione restoration found...