... or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Epilepsy Autism Neurodevelopment GABA Animal models...

... the switch of GABA from depolarizing in young neurons to hyperpolarizing in mature neurons. We describe the expression pattern, regional distribution, and cellular colocalization of KCC2 in the ferret cortex in normal kits and those treated with methylazoxymethanol acetate (MAM). We earlier developed a model...

... or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Isolation rearing Reversal learning Prepulse inhibition Developmental model GABA...

..., recent evidence suggests that cocaine can impair cerebral cortical GABA neuron development and function. We sought to analyze the effects of prenatal cocaine exposure on the number and distribution of GABA and projection neurons (inhibitory interneurons and excitatory output neurons, respectively...

... to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Amygdala Animal model Behavior Fear conditioning Fragile X syndrome GABA Mental illness Fear Emotions Inhibitory circuits National Institutes of Health (NIH...

...Viskasari P. Kalanjati; Stephanie M. Miller; Zoe Ireland; Paul B. Colditz; Stella T. Bjorkman The principal function of the γ-aminobutyric acid (GABA) system in the adult brain is inhibition; however, in the neonatal brain, GABA provides much of the excitatory drive. As the brain develops...

.... Dysplasia Epilepsy GABA Heterotopia Hippocampus Pyramidal cell 29 4 2011 Dev Neurosci 1999;21:374 384 Received: June 29, 1999 Accepted: July 12, 1999 Electrophysiological Responses in vivo of Hippocampal CA1 Pyramidal Neurons in an Animal Model of Neuronal Migration Disorders Bret N...

... mouse Embryonic forebrain Neurodevelopment mRNA splicing regulation Gene expression GABA Interneurons Thalamus Neocortex National Institutes of Health (NIH) 10.13039/100000002 The regulation of gene splicing in neurons (reviewed in Li et al. [ 1 ]), particularly during...

...-MRS GABA Glia Glutamate Glutamine Glycerol-3-phosphate Neurones Trafficking © 1996 S. Karger AG, Basel 1996 Copyright / Drug Dosage / Disclaimer Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form...

... or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Ontogeny Diazepam receptor GABA Benzodiazepine relationship Dev...

... and GABA metabolism were studied throughout neuronal development in culture. The presence of GABAergic neurons in the cultured cell population was demonstrated. There were time-dependent changes in cellular polyamine concentrations and the activities of the enzymes involved in polyamine metabolism. Since...

...John H. Skerritt; Graham A.R. Johnston Developmental changes in the affinity and density of binding sites for the inhibitory neurotransmitter, GABA, were studied in well-washed, frozen-thawed or Triton detergent extracted forebrain and cerebellar membranes from rats of 1 day, 10 days and 12 weeks...

... decarboxylase (+59%), γ-aminobutyric acid (GABA) uptake (+52%), and endogenous GABA levels (+29%) and a decrease in GABA binding (–32%) favor GABA as the neurotransmitter of other cerebellar interneurons. 14 12 2007 © 1982 S. Karger AG, Basel 1982 Copyright / Drug Dosage / Disclaimer Copyright...

..., instructions or products referred to in the content or advertisements. Hippocampus Cortex GABA Interneurons Six3 Dlx5/6 Cre- loxP HGF/SF MET Mouse Original Paper Dev Neurosci 2007;29:143 158 DOI: 10.1159/000096219 Received: December 23, 2005 Accepted: May 10, 2006 Loss of Embryonic MET...

... group had recovered to control levels, but sIPSC frequency remained decreased. These data indicate that the persistently decreased sIPSC frequency result from decreased firing of presynaptic inhibitory interneurons, with only transient possible changes in postsynaptic responses to GABA release. 7...

...Yevgeny Daikhin; Marc Yudkoff The effects of ketone bodies on brain metabolism of glutamate and GABA were studied in three different systems: synaptosomes, cultured astrocytes and the whole animal. In synaptosomes the addition of either acetoacetate or 3-OH-butyrate was associated with diminished...

...H.S. Waagepetersen; I.J. Bakken; O.M. Larsson; U. Sonnewald; A. Schousboe In cerebral cortical neurons, synthesis of the tricarboxylic acid (TCA) cycle-derived amino acids, glutamate and aspartate as well as the neurotransmitter of these neurons, γ-aminobutyrate (GABA), was studied incubating...

..., C3 and C4 positions of both glutamate and the well-resolved C2, C3 and C4 resonances of glutamine and at the C2 and C3 positions of aspartate. GABA was clearly observed for the first time in vivo, suggesting a substantial GABA turnover in the normal human visual cortex. Likewise, lactate C3 labeled...

...:164 179 Received: December 10, 1997 Accepted: January 13, 1998 Age-Dependent Neurobehavioral Plasticity following Forebrain Dopamine Depletions OOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOO Key Words Dopamine D1 receptor D2 receptor Motor behavior Striatum Acetylcholine c-fos GABA GAD65...

.... Using primary cultures established from murine cerebella at different development stages, we analyzed the effects of the neurotransmitter GABA and the neurotrophins BDNF and NT-3 on nNOS expression in developing granule cells. We show a biophasic effect of GABA on nNOS expression, which correlates...