...Marcel Vetter; Markus F. Neurath Background: Crohn’s disease (CD) is a chronic immune-mediated disorder of the gastrointestinal tract. The pathophysiological understanding of this disease is limited and no curative therapy is available so far. Therefore, most patients require long-lasting or even...

.... However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions...

... in lipase substitution therapy include acid-peptic destruction of unprotected enzyme preparations and unphysiological particle sizes of enteric-coated capsules or pellets. Recent data suggest that the adaptation of the diameter of enteric-coated pancreatin micropellets into the range that permits gastric...

... selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged...

... of developing peptic stricture or Barrett’s oesophagus, but the risk factors associated with the development of these significant complications are not well identified. There is also no direct evidence that successful healing of oesophagitis by drug therapy is associated with prevention of local complications...

... for therapy, except in the presence of obstructive gastroduodenal symptoms. With the few data available, it seems correct to say that localized gastroduodenal disease should be treated with standard medical therapy used for more distal disease, with the exception of sulfasalazine and mesalanine with pH...

..., changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when...

... of their antagonism as potentially effective therapy. It was not until the early 1990s that inflammatory cytokines had been characterized sufficiently to suggest their potential role as the most important systemic mediators of acute pancreatitis [ 1 ]. Only in the last year or two has the common ground between...

...X. Rogiers; C. Brunken; M. Malagó; W.T. Knoefel; C.E. Broelsch The only potential curative therapy modality of the hepatocellular carcinoma (HCC) is the complete radical resection. The indication of liver resection becomes problematic in the coincidence of HCC with liver cirrhosis. Only in 1 of 5...