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Keywords: Somatostatin
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Journal Articles
Subject Area:
Gastroenterology
Journal: Digestion
Digestion (2011) 83 (Suppl. 1): 13–18.
Published Online: 10 March 2011
... perception. Recently, it has been revealed that dietary glutamate has many beneficial functions in the gastrointestinal tract. However, the precise mechanism of glutamate sensing still remains unclear. Using primary rat gastric mucosal cell cultures, we demonstrated that somatostatin-secreting D cells...
Journal Articles
Subject Area:
Gastroenterology
Journal: Digestion
Digestion (1997) 58 (3): 249–257.
Published Online: 05 February 2009
... given 25 μg/kg PGE 2 (p < 0.05). The total volume of gastrin/CCK-immunoreactive cells was higher in rats given 25 μg/kg PGE 2 or 50 μg/kg MePGE 2 than in controls (p < 0.05). The volume density of somatostatin-immunoreactive cells increased in rats given 5 μg/kg MePGE 2 , but the total volumes...
Journal Articles
Subject Area:
Gastroenterology
Journal: Digestion
Digestion (1997) 58 (Suppl. 1): 56–58.
Published Online: 05 February 2009
..., instructions or products referred to in the content or advertisements. 1997 Cholecystokinin Somatostatin Glucagon-like peptide 1 Gastric inhibitory polypeptide Paracrine Digestion Digestion I997:58(suppl I ):56 58 woifgmigE. Schmu, Laboratory of Molecular Gastroenterology. 1st Department...
Journal Articles
Subject Area:
Gastroenterology
Journal: Digestion
Digestion (1997) 58 (Suppl. 1): 4–7.
Published Online: 05 February 2009
..., instructions or products referred to in the content or advertisements. 1997 Stomach Gastrin Somatostatin Gastric acid secretion Proinflammatory cytokines Digestion Stomach and Duodenum Digestion I997;58(suppl 4-7 John Del Valle Department o f Internal Medicine, Division o f Gastroenterology...
Journal Articles
Journal Articles
Subject Area:
Gastroenterology
Journal: Digestion
Digestion (1994) 55 (Suppl. 1): 48–51.
Published Online: 05 February 2009
...M. Ebert; H. Friess; H.G. Beger; M.W. Büchler Prognosis in patients with advanced pancreatic cancer is dismal. There has been no effective therapy for these patients so far. Somatostatin and its analogues have been proven to be potent inhibitors of experimental pancreatic cancer. Tumor inhibition...
Journal Articles
Subject Area:
Gastroenterology
Journal: Digestion
Digestion (1994) 55 (Suppl. 1): 35–40.
Published Online: 05 February 2009
... to inhibit exocrine pancreatic secretion perioperatively seems to be a promising concept in the prevention of complications following pancreatic resection. The hormone somatostatin and its synthetic analogue octreotide have been demonstrated to inhibit exocrine pancreatic secretion profoundly, particularly...
Journal Articles
Subject Area:
Gastroenterology
Journal: Digestion
Digestion (1994) 55 (Suppl. 1): 16–19.
Published Online: 05 February 2009
... concept. However, it is not clear whether pancreatic secretion continues during the course of acute pancreatitis. In the present paper experimental and clinical studies are reviewed to evaluate the effect of somatostatin and octreotide treatment in acute pancreatitis. © 1994 S. Karger AG, Basel...
Journal Articles
Subject Area:
Gastroenterology
Journal: Digestion
Digestion (1994) 55 (Suppl. 1): 1–9.
Published Online: 05 February 2009
... on somatostatin as one candidate of several peptides which may physiologically mediate inhibition of pancreatic secretion and on its possible mode of action. Somatostatin probably inhibits pancreatic exocrine secretion by a variety of mechanisms which depend on the species and the type of secretion studied...
Journal Articles
Subject Area:
Gastroenterology
Journal: Digestion
Digestion (1994) 55 (Suppl. 1): 24–28.
Published Online: 05 February 2009
...L. Grauer; J.S. Barkin Somatostatin and its analogue (SMS 201-995, octreotide) have proven to effectively inhibit various gastrointestinal functions including exocrine and neuroendocrine secretion, motility and splanchnic blood flow. The long half-life and the ability to administer the analogue...
Journal Articles
Subject Area:
Gastroenterology
Journal: Digestion
Digestion (1994) 55 (Suppl. 1): 10–15.
Published Online: 05 February 2009
...H. Friess; K. Bordihn; M. Ebert; P. Malfertheiner; T. Kemmer; H.-J. Dennler; M.W. Büchler The somatostatin analogue octreotide (SMS 201-995) is a potent inhibitor of human exocrine pancreatic secretion. In the present study we analyzed the effect of octreotide (3 × 100 μg, daily) given over a time...
Journal Articles
Journal Articles
Subject Area:
Gastroenterology
Journal: Digestion
Digestion (1993) 54 (Suppl. 1): 41–46.
Published Online: 05 February 2009
... is a promising concept in the prevention of complications. The hormone somatostatin and its synthetic analogue octreotide have been shown to profoundly inhibit exocrine pancreatic secretion, particularly the secretion of proteases. In a randomized, placebo-controlled, multicenter double-blind trial we analyzed...
Journal Articles
Journal Articles
Subject Area:
Gastroenterology
Journal: Digestion
Digestion (1993) 54 (Suppl. 1): 47–52.
Published Online: 05 February 2009
... and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. 1993 Somatostatin Octreotide Short bowel syndrome Dumping syndrome M.J.G. Farthing Departments...
Journal Articles
Subject Area:
Gastroenterology
Journal: Digestion
Digestion (1993) 54 (Suppl. 1): 20–26.
Published Online: 05 February 2009
...John P. Cello; Mary F. Chan Somatostatin and its analogue, octreotide, produce dramatic decreases in splanchnic arterial blood flow and portal venous pressure while preserving cardiac output and systemic blood pressure. A limited number of prospective randomized clinical trials of somatostatin...
Journal Articles
Subject Area:
Gastroenterology
Journal: Digestion
Digestion (1993) 54 (Suppl. 1): 9–13.
Published Online: 05 February 2009
...P. Marbach; U. Briner; M. Lemaire; A. Schweitzer; T. Terasaki Somatostatin and its octapeptide analogue octreotide (Sandostatin®) have a similar high affinity for specific receptors with IC 50s in the sub-nanomolar range. Hence, the striking superiority of octreotide in vivo, which includes...
Journal Articles
Subject Area:
Gastroenterology
Journal: Digestion
Digestion (1993) 54 (Suppl. 1): 68–71.
Published Online: 05 February 2009
.... By contrast, insulinomas are more resistant to somatostatin agonist therapy. In the Zollinger-Ellison syndrome, octreotide is effective in alleviating symptoms and in reducing serum gastrin levels. However, its use in this syndrome has been superceded by omepra-zole. Radioiodine-labelled octreotide has been...
Journal Articles
Subject Area:
Gastroenterology
Journal: Digestion
Digestion (1993) 54 (Suppl. 1): 30–32.
Published Online: 05 February 2009
...M. Moroni; R. Esposito; M. Cernuschi; F. Franzetti; G.P. Carosi; G.P. Fiori We evaluated the effect of octreotide, a long-acting synthetic analogue of native somatostatin, on bowel frequency in 13 patients with AIDS-associated refractory diarrhoea. Cryptosporidium enteritis and cytomegalovirus...
Journal Articles
Subject Area:
Gastroenterology
Journal: Digestion
Digestion (1993) 54 (Suppl. 1): 76–83.
Published Online: 05 February 2009
...J.C. Reubi; E. Krenning; S.W.J. Lamberts; L. Kvols Somatostatin receptors (SS-R) have been identified in membrane homoge-nates or tissue sections from several hundred human tumors. SS-R have been found in most neuroendocrine tumors, i.e. GH- and TSH-producing pituitary tumors, endocrine...