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1-20 of 23
Keywords: Prognosis
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Journal Articles
Characteristics and Prognosis of Sporadic Neoplasias Detected in Patients with Ulcerative Colitis
Available to PurchaseSubject Area:
Gastroenterology
Noriko Yamamoto, Ken Yamashita, Yudai Takehara, Shin Morimoto, Fumiaki Tanino, Yuki Kamigaichi, Hidenori Tanaka, Koji Arihiro, Fumio Shimamoto, Shiro Oka
Journal:
Digestion
Digestion (2024) 105 (3): 213–223.
Published Online: 28 February 2024
... studies have described the characteristics of SNs in patients with UC. Therefore, this study aimed to evaluate the clinical features and prognosis of SNs in patients with UC. Methods: A total of 141 SNs in 59 patients with UC, detected by surveillance colonoscopy at Hiroshima University Hospital between...
Journal Articles
Classification of Colorectal Cancer Subtypes Based on Endoplasmic Reticulum Stress
Available to PurchaseSubject Area:
Gastroenterology
Journal:
Digestion
Digestion (2024) 105 (2): 107–130.
Published Online: 23 November 2023
... used to screen and validate genes related to stage and prognosis of CRC. Twenty thousand five hundred thirty samples from the TCGA database validated the ERS genes related to prognosis. PPI network construction and coexpression analysis were used to investigate the correlation of genes...
Journal Articles
Subject Area:
Gastroenterology
Kentaro Ochiai, Kazushige Kawai, Hiroaki Nozawa, Kazuhito Sasaki, Manabu Kaneko, Koji Murono, Shigenobu Emoto, Hiroaki Ishii, Hirofumi Sonoda, Shinichi Yamauchi, Kenichi Sugihara, Soichiro Ishihara
Journal:
Digestion
Digestion (2021) 102 (6): 911–920.
Published Online: 14 July 2021
..., instructions or products referred to in the content or advertisements. 2021 Multiple primary malignancies Multiple cancers Colorectal cancer Prognosis Colorectal cancer (CRC) is the third most common malignant disease worldwide and the second most common cause of cancer mortality [ 1...
Journal Articles
Predictive Factors for Short-Term Survival after Non-Curative Endoscopic Submucosal Dissection for Early Gastric Cancer
Available to PurchaseSubject Area:
Gastroenterology
Tomohiro Shimada, Taku Yamagata, Yoshihide Kanno, Tetsuya Ohira, Yoshihiro Harada, Yoshiki Koike, Megumi Tanaka, Daichi Komabayashi, Takeshi Shimizu, Haruka Okano, Shohei Suzuki, Kei Ito
Journal:
Digestion
Digestion (2021) 102 (4): 630–639.
Published Online: 15 September 2020
... nutritional risk index Prognosis Various attempts to detect and treat gastric cancer early have been made. In Japan, more than half of the gastric cancers are detected in early stages as a result of the development of nationwide screening programs and the prevalence of high-resolution endoscopes [ 1...
Journal Articles
Enhancer of Zeste Homolog 2 in Colorectal Cancer Development and Progression
Available to PurchaseSubject Area:
Gastroenterology
Sebastian C.B. Bremer, Lena-Christin Conradi, Nicolae-Catalin Mechie, Ahmad Amanzada, Eirini Mavropoulou, Julia Kitz, Michael Ghadimi, Volker Ellenrieder, Philipp Ströbel, Elisabeth Hessmann, Jochen Gaedcke, Hanibal Bohnenberger
Journal:
Digestion
Digestion (2021) 102 (2): 227–235.
Published Online: 06 November 2019
... mechanisms of carcinogenesis has led to new therapeutic approaches during the last years. Enhancer of zeste homolog 2 (EZH2) is one central epigenetic silencer of the polycomb repressor complex 2 (PRC2) that is already in clinical use as a novel drug target and is associated with poorer prognosis in several...
Journal Articles
Increasing Heme Oxygenase-1-Expressing Macrophages Indicates a Tendency of Poor Prognosis in Advanced Colorectal Cancer
Available to PurchaseSubject Area:
Gastroenterology
Shingo Kimura, Naing Ye Aung, Rintaro Ohe, Mitsuhiro Yano, Toshio Hashimoto, Tsukasa Fujishima, Wataru Kimura, Mitsunori Yamakawa
Journal:
Digestion
Digestion (2020) 101 (4): 401–410.
Published Online: 21 May 2019
...Shingo Kimura; Naing Ye Aung; Rintaro Ohe; Mitsuhiro Yano; Toshio Hashimoto; Tsukasa Fujishima; Wataru Kimura; Mitsunori Yamakawa Background: Many cancers express heme oxygenase-1 (HO-1) at a higher frequency than healthy tissues, and this elevated expression is associated with cancer prognosis...
Journal Articles
Clinical Outcomes of Patients with Small Rectal Neuroendocrine Tumors Treated Using Endoscopic Submucosal Resection with a Ligation Device
Available to PurchaseSubject Area:
Gastroenterology
Maiko Takita, Eiji Sakai, Tomomi Nakao, Yoshiaki Kimoto, Rindo Ishii, Takafumi Konishi, Sakaya Ueno, Keisuke Kanda, Ryoju Negishi, Takashi Muramoto, Hirotsugu Hashimoto, Teppei Morikawa, Nobuyuki Matsuhashi, Ken Ohata
Journal:
Digestion
Digestion (2019) 99 (1): 72–78.
Published Online: 14 December 2018
... during the follow-up period in 77 patients with a curative resection, 9 patients who received additional surgery, and 50 patients with non-curative resections. Conclusion: ESMR-L is an easy, safe and effective treatment for rectal NETs <10 mm in diameter, and the prognosis of patients seems to be good...
Journal Articles
Low Skeletal Muscle Mass before Salvage-Line Chemotherapy Is a Poor Prognostic Factor in Patients with Refractory Metastatic Colorectal Cancer
Available to PurchaseSubject Area:
Gastroenterology
Yuji Miyamoto, Yukiharu Hiyoshi, Takahiko Akiyama, Yuki Kiyozumi, Kojiro Eto, Nagai Yohei, Shiro Iwagami, Yoshifumi Baba, Naoya Yoshida, Hideo Baba
Journal:
Digestion
Digestion (2019) 99 (1): 79–85.
Published Online: 14 December 2018
... biomarkers to identify patients likely to respond to salvage-line chemotherapy. Cachexia Salvage-line chemotherapy Skeletal muscle Prognosis Toxicity In this study, we demonstrated that low skeletal muscle mass before salvage-line chemotherapy was significantly associated with shorter OS...
Journal Articles
Long Interspersed Element-1 Methylation Level as a Prognostic Biomarker in Gastrointestinal Cancers
FreeSubject Area:
Gastroenterology
Yoshifumi Baba, Taisuke Yagi, Hiroshi Sawayama, Yukiharu Hiyoshi, Takatsugu Ishimoto, Masaaki Iwatsuki, Yuji Miyamoto, Naoya Yoshida, Hideo Baba
Journal:
Digestion
Digestion (2018) 97 (1): 26–30.
Published Online: 01 February 2018
... approximately 17% of the human genome, the extent of LINE-1 methylation is regarded as a surrogate marker of global DNA methylation. In a variety of gastrointestinal (GI) cancers, LINE-1 hypomethylation is strongly associated with a poor prognosis, supporting its potential role as a prognostic biomarker...
Journal Articles
Clinicopathological Features of Colorectal Cancer Patients Under the Age of 50: Recent Experience and Case-Control Study of Prognosis in a Japanese Cohort
Available to PurchaseSubject Area:
Gastroenterology
Yuzo Nagai, Keisuke Hata, Kazushige Kawai, Koji Murono, Koji Yasuda, Kensuke Otani, Takeshi Nishikawa, Toshiaki Tanaka, Tomomichi Kiyomatsu, Hiroaki Nozawa, Hironori Yamaguchi, Soichiro Ishihara, Toshiaki Watanabe
Journal:
Digestion
Digestion (2016) 93 (4): 272–279.
Published Online: 18 May 2016
... is increasing, indicating an urgent need for understanding young-onset CRC. This study serves to clarify the characteristics and prognosis of young CRC patients. Methods: Using a detailed database, various clinicopathological findings including symptoms, family history and prognosis of 70 young CRC patients...
Journal Articles
Well-Differentiated Neuroendocrine Neoplasia: Relapse-Free Survival and Predictors of Recurrence after Curative Intended Resections
Available to PurchaseSubject Area:
Gastroenterology
P. Dieckhoff, H. Runkel, H. Daniel, D. Wiese, A. Koenig, V. Fendrich, D.K. Bartsch, R. Moll, D. Müller, R. Arnold, T. Gress, A. Rinke
Journal:
Digestion
Digestion (2014) 90 (2): 89–97.
Published Online: 04 September 2014
..., instructions or products referred to in the content or advertisements. 2014 Neuroendocrine tumor Prognosis Recurrence Proliferation rate Microangioinvasion Neuroendocrine tumors (NETs) are potentially malignant neoplasms. Their incidence is increasing [ 1, 2, 3 ]. Rising awareness...
Journal Articles
Tumor-Infiltrating FoxP3+ Tregs and CD8+ T Cells Affect the Prognosis of Hepatocellular Carcinoma Patients
Available to PurchaseSubject Area:
Gastroenterology
Journal:
Digestion
Digestion (2012) 86 (4): 329–337.
Published Online: 28 November 2012
... or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. 2012 Carcinoma Hepatocellular FoxP3 CD8 Angiogenesis Prognosis Hepatocellular carcinoma (HCC) is one of the most common malignant tumors in the world, especially among...
Journal Articles
Serum Levels of Soluble Adhesion Molecules as Prognostic Factors for Acute Liver Failure
Available to PurchaseSubject Area:
Gastroenterology
Atsuyuki Ohnishi, Yasuhiro Miyake, Hiroshi Matsushita, Kazuyuki Matsumoto, Akinobu Takaki, Tetsuya Yasunaka, Kazuko Koike, Fusao Ikeda, Hidenori Shiraha, Kazuhiro Nouso, Kazuhide Yamamoto
Journal:
Digestion
Digestion (2012) 86 (2): 122–128.
Published Online: 27 July 2012
... the prognosis of ALF. In patients with sepsis or septic shock, serum sICAM- 1 levels have been reported to be correlated with serum bilirubin levels [ 7, 8 ]. Furthermore, in patients with alcoholic liver cirrhosis, serum sICAM-1 levels have been shown to be correlated with prothrombin activities and serum...
Journal Articles
Effect of Low-Dose Gemcitabine on Unresectable Pancreatic Cancer in Elderly Patients
Available to PurchaseSubject Area:
Gastroenterology
Kazuyuki Matsumoto, Yasuhiro Miyake, Hironari Kato, Hirofumi Kawamoto, Atsushi Imagawa, Tatsuya Toyokawa, Morihito Nakatsu, Masaharu Ando, Mamoru Hirohata, Kazuhide Yamamoto
Journal:
Digestion
Digestion (2011) 84 (3): 230–235.
Published Online: 23 August 2011
... were associated with the prognosis. Conclusions: Low-dose GEM may improve the prognosis of elderly patients with unresectable pancreatic cancer. Furthermore, frequencies of severe toxicity seem lower in patients treated with low-dose GEM compared with previous reports. 21 12 2010 28 06 2011...
Journal Articles
Expression Levels of Insulin-Like Growth Factor-1 and Multidrug Resistance-Associated Protein-1 Indicate Poor Prognosis in Patients with Gastric Cancer
Available to PurchaseSubject Area:
Gastroenterology
Journal:
Digestion
Digestion (2009) 80 (3): 148–158.
Published Online: 28 August 2009
... < 0.01). IGF-1R and MPR-1 over-expression were correlated with poor prognosis of GC (p < 0.01). 102 patients receiving adjuvant FOLFOX-4 chemotherapy who co-expressed IGF-1R/MRP-1 had poor prognosis (p < 0.05). Conclusions: The levels of co-expression of IGF-1R/MRP-1 in GC may predict...
Journal Articles
Factors Influencing Long-Term Survival in Patients with T3 Gallbladder Adenocarcinoma
Available to PurchaseSubject Area:
Gastroenterology
Journal:
Digestion
Digestion (2009) 79 (3): 151–157.
Published Online: 30 March 2009
... prognostic factor in predicting the long-term prognosis of T0–T4 GBA; however, the result is preliminary due to the limited number of patients. Further studies with a large number of patients are necessary to confirm our result. 27 11 2008 2 06 2009 30 03 2009 © 2009 S. Karger AG, Basel...
Journal Articles
Historical Background and Natural History of Carcinoids
Available to PurchaseSubject Area:
Gastroenterology
Journal:
Digestion
Digestion (1994) 55 (Suppl. 3): 3–10.
Published Online: 05 February 2009
... endocrine tumors, and others include a large variety of neuroendocrine tumors. In this review the following definition is given: Carcinoids are tumors of the diffuse endocrine system which are either benign or neoplasms with a more favorable prognosis than carcinomas; they are characterized by a typical...
Journal Articles
Standards and Perspectives in the Diagnosis and Treatment of Pancreatic Adenocarcinoma
Available to PurchaseSubject Area:
Gastroenterology
Journal:
Digestion
Digestion (1996) 57 (Suppl. 1): 34–35.
Published Online: 05 February 2009
...U. Sulkowski Despite certain advances, the overall prognosis for pancreatic carcinoma has remained extremely dismal. Even now, not more than 5% of all patients diagnosed as having pancreatic carcinoma survive 5 years. With this background, the standards and new developments for this entity...
Journal Articles
Prognosis of Gastric Carcinoid Tumours
Available to PurchaseSubject Area:
Gastroenterology
Journal:
Digestion
Digestion (1995) 56 (6): 455–462.
Published Online: 05 February 2009
...S. Rappel; A. Altendorf-Hofmann; M. Stolte With the aim of evaluating the prognosis of carcinoid tumours of the stomach, the tumours were classified into subtypes on the basis of the type of gastritis, and a comparison made of the type of treatment, metastasizing rate, and the survival rates...
Journal Articles
Prognostic Value of the Intravenous 14 C-Aminopyrine Breath Test Compared to the Child-Pugh Score and Serum Bile Acids in 84 Cirrhotic Patients
Available to PurchaseSubject Area:
Gastroenterology
Journal:
Digestion
Digestion (1991) 50 (3-4): 212–218.
Published Online: 04 February 2009
..., FRG Key Words. Intravenous aminopyrine breath test Serum bile acids Child-Pugh score Liver cirrhosis Prognosis Abstract. The prognostic value of the intravenous MC-aminopyrine breath test (ABT) in liver cirrhosis was compared to that of the well-established multiparametric Child-Pugh...
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