.... Different degrees of mucosal damage were produced using ethanol and by varying the concentration (5–100%) and the exposure period (1–60 min). Exposure of the stomach for 10min to ethanol induced hemorrhagic lesions and a reduction in the transmucosal potential difference (PD); its severity and its magnitude...

...H.D. Janisch; V.F. Eckardt Oesophageal transmural potential difference measurements have been used to localize the oesophagogastric mucosal junction and to detect reflux-induced mucosal damage. The current study confirms that such measurements lead to reproducible results when they are used...

...) or nitric oxide (NO) production [ 3, 14 ]. The methods used for determining transmucosal potential difference (PD) and gastric perfusion were as described in our previous papers [ 11, 12 ]. Briefly, under urethane anesthetized conditions (1.25 g/kg, i.p.), the abdomen was opened through a midline...