.... The remaining rats in these groups served as controls. Half of the rats in the fourth group were given subcutaneous injections with pentagastrin, 250 μg/kg body weight, twice daily for 90 days. The remaining rats in this group received vehicle only. At the end of the treatment period, all animals were killed...

... to in the content or advertisements. 1995 Circadian rhythm Dog Gastric acidity Gastric fistula Gastropexy Intragastric pH-metry Pentagastrin Surgical implantation Original Paper Digestion 1995;56:35-40 S. Postius U. Brauer Department o f Pharmacology, Byk Gulden Pharmaceuticals, Konstanz. FRG Loss...

... m M oleyl alcohol. Oleic acid significantly inhibited the gastric acid secretion stimulated by pentagastrin (100 ng/kg/h) and increased the levels of secretin in plasma. The effect of oleyl alcohol was insignificant. It is concluded that the carboxyl group of the fat molecule has an important role...

... epithelial cells were isolated and counted. Gastric mucous epithelial cells were enriched from the total gastric fundic cell population and cultured for 6 days in the absence or presence of hormones (epidermal growth factor and pentagastrin). We found that omeprazole treatment for 1–6 weeks significantly (p...

... gastric acid secretion. To study their individual and combined effects on pentagastrin-stimulated (0.1 μg/kg/h from – 90 to 120 min) gastric volume, acid and chloride output, on separate occasions, synthetic human GIP (1 pmol/kg/min) and/or GLP-1 [7-36 amide] (0.3 pmol/ kg/min) or placebo (0.9% NaCl...

...C. Cederberg; T. Lind; K. Röhss; L. Olbe The effect of 5 days of once-daily dosing with 20 mg p.o. and 40 mg i.v. omeprazole on pentagastrin-stimulated acid secretion was studied in 8 patients with duodenal ulcer. In addition they also received a 10-mg i.v. dose on day 6 during the oral treatment...

... in the liver. This study was designed to examine the action of EGF administered intraduodenally (i.d.), intravenously (i.v.) or intraportally (i.p.) on pentagastrin-stimulated gastric and pancreatic secretion and to determine the role of liver in the EGF uptake. In conscious dogs with gastric and pancreatic...

...O. Olsen; J. Christiansen In 6 healthy volunteers we investigated the effect of secretin and peptide YY (PYY) on gastric acid secretion stimulated by pentagastrin (100 ng/kg/h). Secretin (0.05 CU/ kg/h) and PYY (10.0 pmol/kg/h) were given intravenously either alone or in combination. Given alone...

... with a gastric fistula during a background stimulation of gastric secretion by continuous infusions of pentagastrin, bethanechol or histamine. During infusion of pentagastrin or histamine, BRL 24924, by itself, influenced gastric secretion with stimulation during a low potent background stimulation...

...C. Loguercio; D. Costato; C. Del Vecchio Blanco Previous works have documented that pentagastrin has a stimulatory effect on salivary secretion. In this paper, we have studied the action of caerulein, a peptide that has an active gastrin-like terminal tetrapeptide, on salivary secretion in man. Our...

...Carmela Loguercio; Ilario de Sio; Marco Romano; Camillo del Vecchio Blanco; Mario Coltorti Intravenous infusion of pentagastrin increases salivary secretion progressively at doses from 1 to 4 μg/kg body weight/h. Pentagastrin also stimulates salivary secretion of amylase. Simultaneous...

...R. Rolston; M. Ghiglione; A.J. Bacarese-Hamilton; L.O. Uttenthal; S.R. Bloom Although the purified porcine enteroglucagons glicentin and oxyntomodulin inhibit pentagastrin-stimulated gastrin acid secretion when given parenterally to rats, it is not known whether the postprandial rise in endogenous...

... secretion in addition to that produced by released gastrin. In 4 gastric fistula (GF) and Heidenhain pouch (HP) cats, 160 pmol·kg -1 ·h -1 i.v. GRP produced a GF and HP acid response that amounted to 22 and 13%, respectively, of the maximal acid response to pentagastrin, with no rise in serum gastrin...

...I. Whitehouse; C. Beglinger; H. Bally; K. Gyr The aim of this study was to identify the somatostatin (SST-14) dose dissolved in 0.1 % human albumin solution equivalent to the commonly used therapeutic dose (3.5 μg kg -1 h -1 ) dissolved in saline in inhibiting pentagastrin-stimulated gastric acid...

...S. Emås; G. Nylander; B. Wallin The dose-response (DR) curves for acid output to intravenous pentagastrin were determined by two techniques in conscious rats with chronic gastric fistula. With the continuous DR technique, the dose of pentagastrin was doubled each hour; with the single DR technique...

...Andreas Aly; Sverre Emås The acid and pepsin responses to increasing doses of i.v. pentagastrin (0.01, 0.02, 0.1, 2.0 and 8.0 μg·kg -1 •h -1 ) were determined by gastric aspiration in 15 male duodenal ulcer (DU) patients and 11 male age-matched healthy controls (C). The lowest dose was infused...

...M. Mogard; S. Emås; G. Nylander; B. Wallin; C. Wallin The effects of upper small intestinal perfusion with iso-osmolar or hyperosmolar polyethylene glycol (PEG) solutions on maximal gastric acid secretion stimulated by intravenous pentagastrin was investigated in Sprague-Dawley rats. The animals...

...Håkan Blom Ulcers were produced in the gastric mucosa in rats. After 90 days of healing, one group of animals was given pentagastrin and carbacholine via continuous subcutaneous infusion. After 1 h the animals were killed and the wounds and normal mucosa beside the wounds were prepared for electron...

...W. Padovan; R.A. Godoy; U.G. Meneghelli; R.O. Dantas; R.B. Oliveira; L.E.A. Troncon Gastric acid and pepsin secretory responses to graded doses of pentagastrin were measured in 12 Chagas’ disease patients and 18 control subjects, and in 7 Chagas’ disease patients and 6 controls the study...

...U.G. Meneghelli; R.A. Godoy; R.B. Oliveira; J.C.M., Jr Santos; R.O. Dantas; L.E.A. Troncon In order to evaluate the effect of pentagastrin on the motor activity of the sigmoid and rectum in patients with Chagas’ disease, manometric studies were performed on 22 chagasic patients, 11 without and 11...