.... Parietal cell volume density was about 15 % in both the DU patients and in the controls; in the ZE patients, slightly but not significantly higher values were recorded. No significant change was observed during omeprazole treatment. © 1986 S. Karger AG, Basel Copyright / Drug Dosage / Disclaimer...

...Wolfgang Schepp; Kerstin Dehne; Thomas Riedel; Johanna Schmidtler; Kirsten Schaffer; Meinhard Classen We have previously shown that in highly enriched rat gastric parietal cells the intestinal peptide hormones oxyntomodulin and glucagon-like peptide-2 (GLP-2) compete for receptor-binding...

..., the parietal cells were morphologically normal, and there were no changes of pattern or any increase in the number of argyrophil enterochromaffin-like cells compared to the control animals. In the plasma samples collected 24 h after dosing, there were no significant differences in either basal or meal...

... occupied by surface mucus cells, and also significantly decreased the volume fraction of the parietal cells. Digestion 1990;45:212-216 © 1990 S. Karger AG, Basel 0 0 1 2 - 2 8 2 3 /9 0 /0 4 5 4 - 0 2 1 2S2.75/0 Prostaglandins and the Dog Stomach: Effects of Misoprostol on the Proportion of Mucosa to Muscle...

...Johanna Schmidtler; Wolfgang Schepp; Volker Schusdziarra; Meinhard Classen We investigated the hypothesis of a direct effect of amino acids on gastric parietal cells. [ 14 C]aminopyrine uptake into isolated enriched rat parietal cells served as a quantitative index of H + production. Cells were...

... (H + +K + )ATPase inhibitors timoprazole and omeprazole revealed that the potency of timoprazole was similar to the one of clozapine while omeprazole was intermediate between thioridazine and chlorpromazine. Pirenzepine was ineffective. [14C]Aminopyrine uptake Parietal cells Tricyclic...

... microscopy. Stereological analyses of regenerating parietal cells from the wounds revealed that stimulation by the secretagogues increased the secretory surface density by some 76%. pH studies were performed in the wounds in another group of animals after the same stimulation as above, and it was found...

.... The rise in circulating gastrin concentration during infusion of a standard dose of gastrin was 1,340 pg ml -1 in the conscious cat. Comparable studies in man and dog give values of 900 and 300 pg ml -1 , respectively. Based on these observations, the sensitivity of the parietal cells to gastrin...