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Keywords: NSAIDs
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Journal Articles
Subject Area:
Gastroenterology
Journal: Digestion
Digestion (2014) 90 (2): 81–88.
Published Online: 04 September 2014
... with necroinflammatory hepatocellular injury (most frequently caused by NSAIDs), transporter staining was normal in areas where hepatocyte morphology was preserved. Due to hepatocyte necrosis and the reduction of the hepatocyte number, overall transporter expression was reduced without a reduction in transporter...
Journal Articles
Subject Area:
Gastroenterology
Journal: Digestion
Digestion (2012) 85 (2): 131–135.
Published Online: 19 January 2012
...Yumiko Nagano; Hirofumi Matsui; Masato Tamura; Osamu Shimokawa; Yukio Nakamura; Tsuyoshi Kaneko; Ichinosuke Hyodo Non-steroidal anti-inflammatory drugs (NSAIDs) often cause gastrointestinal complications such as gastric ulcers and erosions. Recent studies on the pathogenesis have revealed...
Journal Articles
Journal Articles
Subject Area:
Gastroenterology
Journal: Digestion
Digestion (1992) 53 (3-4): 129–133.
Published Online: 04 February 2009
...S. Levi; R.A. Goodlad; C.Y. Lee; G. Stamp; M.J. Walport; N.A. Wright; H.J.F. Hodgson We demonstrate that, in patients taking non-steroidal anti-inflammatory drugs (NSAIDs), there is inhibition of the proliferation of mucosal cells that normally leads to healing of duodenal ulcers. A microdissection...
Journal Articles
Subject Area:
Gastroenterology
Journal: Digestion
Digestion (2006) 73 (Suppl. 1): 136–150.
Published Online: 27 February 2006
...Ángel Lanas; Carmelo Scarpignato Upper gastrointestinal (GI) complications are well-recognized adverse events associated with non-steroidal anti-inflammatory drug (NSAID) use. However, NSAID-induced damage to the distal GI tract is also common and more frequent than previously recognized...
Journal Articles
Subject Area:
Gastroenterology
Journal: Digestion
Digestion (2004) 69 (Suppl. 1): 25–33.
Published Online: 10 March 2004
...Jay L. Goldstein The use of non-selective non-steroidal anti-inflammatory drugs (NSAIDs) and/or aspirin is associated with upper gastrointestinal (UGI) tract injury, particularly in high-risk patients (e.g. those with prior upper GI ulcers and ulcer complications, individuals ≧ 65 years, or those...
Journal Articles
Subject Area:
Gastroenterology
Journal: Digestion
Digestion (2004) 69 (1): 10–19.
Published Online: 10 March 2004
...Fabiola Delcò; Pierre Michetti; Christoph Beglinger; Michael Fried; Thomas D. Szucs Background and Aims: The well-recognized gastrointestinal toxicity of NSAIDs ranges from mild symptoms to severe complications requiring medical attention and leading to work loss. The present study evaluates...