... with megacolon, and 11 control subjects. Pentagastrin had a stimulating effect on the sigmoid and rectum in control subjects as well as in chagasic patients without megacolon. In chagasic patients with megacolon, pentagastrin had no effect on sigmoid or rectum motility, probably as a result of the intrinsic...

...I. Taylor; C. Darby; P. Hammond A number of parameters of ano-rectal function were measured in 10 patients with adult megacolon and the values compared to those in an age- and sex-matched group of normal volunteers. The absence of inhibition of force in the anal canal on rectal distention...

... by toxic megacolon. It is suspected that the neurodegenerative alterations in these diseases are toxically induced. 20 09 1976 30 11 1976 1 07 1977 Enteritis, regional Ganglia, autonomic Megacolon Myenteric plexus Digestion 15: 482-496 (1977) Intramural Ganglion Cell...