...L. Lundell; C.H. Malbert; M. Anvari; P. Yu; G.G. Jamieson The mechanisms involved in the relaxation of the lower oesophageal sphincter induced by distension of the oesophagus and different parts of the stomach, were studied in an anaesthetized porcine model. A computer technique was developed...

... to identify the oesophagogastric mucosal junction. In normal persons this anatomical structure is always localized within or below the lower oesophageal sphincter. In contrast potential difference measurements of the distal oesophagus show marked intraindividual variations and no correlation was found between...

...J.S. Davison A rapid pull-through technique was used to measure lower oesophageal sphincter pressure before and immediately after swallowing. Often no high pressure zone could be detected after a swallow although sometimes an attenuated pressure profile persisted, associated with weakly developed...

... motility probe and the Ingold combined stomach pH electrode, measurements were made of the lower oesophageal sphincter (LES) pressure and length, swallowing responses, reflux and clearance of acid. The presence of varices was associated with an increase in LES length and reduced lower oesophageal...

... blockers that relax the lower oesophageal sphincter (LOS) may increase gastro-oesophageal reflux and the risk of oesophageal adenocarcinoma. We conducted a case-control study to examine the association between the use of NSAIDs and drugs which relax the LOS and the risk of oesophageal cancer. Methods...

... was to investigate whether luminal NO can influence oesophageal smooth muscle performance, lower oesophageal sphincter (LOS) function or gastric and oesophageal acid exposure. Methods: Eleven healthy volunteers and 9 patients with chronic gastro-oesophageal reflux disease (GORD) received a diet deprived of nitrate...