... not provide useful information on disease activity [ 37 ]. Fecal lactoferrin Fecal biomarkers Fecal markers Crohn’s disease Inflammatory bowel diseases Crohn’s disease (CD) symptoms are often nonspecific. Therefore, noninvasive markers of disease activity are often employed to optimize...

... in the treatment of inflammatory bowel diseases (IBDs) for over 20 years. Summary: This review article aimed to provide an update on recent advances in TNF antagonist therapy for IBDs. Key Messages: Their position in the treatment algorithm has evolved to “rapid step-up therapy” or “top-down therapy” according...

...Benjamin Misselwitz; Pascal Juillerat; Michael Christian Sulz; Britta Siegmund; Stephan Brand; on behalf of Swiss IBDnet, an official working group of the Swiss Society of Gastroenterology Background: Treatment of inflammatory bowel diseases (IBD) has tremendously improved during the last 20 years...

..., Suita, Japan; f Core Research for Evolutional Science and Technology, Japan Agency for Medical Research and Development, Tokyo, Japan; g Department of Therapeutics for Inflammatory Bowel Diseases, Graduate School of Medicine, Osaka University, Suita, Japan Keywords Crohn s disease · Human colon...

... (SHAP) in inflammatory bowel disease (IBD) pathogenesis and its potential as a novel IBD biomarker. Methods: We studied the SHAP expression in a mouse model of colitis and in human intestinal samples of IBD and compared serum concentrations with normal controls. Results: SHAP was expressed...

...Takashi Nagaishi; Taro Watabe; Nisha Jose; Arisa Tokai; Toshimitsu Fujii; Katsuyoshi Matsuoka; Masakazu Nagahori; Kazuo Ohtsuka; Mamoru Watanabe Prolonged inflammatory bowel diseases (IBD) may lead to colitis-associated carcinogenesis (CAC). Previous studies had shown that nuclear factor-κB (NF-κB...

... the interstitium at the deepest invasive margin of the cancer is seen (budding: positive). The second session was about the diagnosis of inflammatory disease by biopsy. The target included inflammatory bowel diseases and esophagitis. Diagnosis of infectious enteritis and non-steroidal anti...

... of inflammatory bowel diseases (IBD) as well as myelodysplastic syndrome (MDS), the mechanisms of how these cytogenetic abnormalities cause intestinal inflammation are poorly understood. Methods and Results: A 55-year-old man with a 3-month history of watery diarrhea, fever and abdominal pain was admitted. Blood...

...Antonella Tragnone; Carlo Hanau; Gabriele Bazzocchi; Giorgio Assuero Lanfranchi Recently, in Bologna, an inflammatory bowel disease incidence of 7.7/10 5 /year has been calculated, about one third of that reported in Northern Europe, confirming the existence of a ‘North-South gradient’. A first...

... Immunoblotting Inbred mice Inflammatory bowel diseases Digestion 1991;49:106-119 © 1991 S. Kargcr AG, Basel 0012-2823/91 /0492-0106S2.75/0 Immunopathological and Immunochemical Analysis of Autoimmune Enterocolitis in Mice N. Després, M S. Nemirovsky Département d'Anatomie et de Biologie cellulaire. Faculté...

... of chronic inflammatory bowel diseases. We studied plasma elastase in 44 patients suffering from Crohn’s disease or ulcerative colitis. Plasma levels were significantly higher in these patients compared to 7 patients with noninflammatory bowel diseases or 53 healthy controls. Elevated plasma levels were more...

... and biochemical markers reflecting disease activity and to examine changes in TFF1–3 in patients with inflammatory bowel disease (IBD) before and during high-dose prednisolone treatment and tapering . Methods: Serum concentrations of TFF1–3 were quantified in 48 ulcerative colitis (UC) and 50 Crohn’s disease (CD...

...Athanasios G. Pallis; Ioannis G. Vlachonikolis; Ioannis A. Mouzas Given the early onset, the chronic and recurrent nature of their disease and their normal life expectancy, patients with inflammatory bowel disease (IBD) may need considerable health care. The purpose of this study is to validate...