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1-18 of 18
Keywords: Inflammation
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Journal Articles
Effects of Colchicine on NSAID-Induced Severe Small Intestinal Damage: A Pilot Study
Available to PurchaseSubject Area:
Gastroenterology
Koji Otani, Toshio Watanabe, Akira Higashimori, Yuji Nadatani, Yasuaki Nagami, Koichi Taira, Kentaro Inui, Yasuhiro Fujiwara
Journal:
Digestion
Digestion (2021) 102 (5): 803–808.
Published Online: 17 November 2020
... of liver enzyme levels after colchicine treatment (shown in Fig. 4 ). No other adverse events including changes in blood tests and clinical symptoms were observed. Capsule endoscopy Colchicine Inflammation Nonsteroidal anti-inflammatory drugs Small intestine Nonsteroidal anti...
Journal Articles
Monocyte-Derived Hepatocyte-Like Cell Test: A Novel Tool for in vitro Identification of Drug-Induced Liver Injury in Patients with Herbal or Dietary Supplements
Available to PurchaseSubject Area:
Gastroenterology
Sabine Weber, Grace L.H. Wong, Vincent W.S. Wong, Andreas Benesic, Henry L.Y. Chan, Alexander L. Gerbes
Journal:
Digestion
Digestion (2021) 102 (4): 650–653.
Published Online: 20 July 2020
... from any ideas, methods, instructions or products referred to in the content or advertisements. 2020 Liver Inflammation Drug-induced liver injury Herbal and dietary supplements Hepatotoxicity Herbal and dietary supplements (HDS) can cause idiosyncratic drug-induced liver injury...
Journal Articles
Subject Area:
Gastroenterology
Journal:
Digestion
Digestion (2018) 98 (1): 19–25.
Published Online: 19 April 2018
...). PAR2 activation on epithelial cells induces epithelial IL-8 secretion and initiates mucosal inflammation. Methods: A human primary esophageal epithelial cell model was established to investigate the effects of repeated stimulation with weakly acidic solutions and subsequent PAR2 activation. After...
Journal Articles
Anthocyanins Prevent Colorectal Cancer Development in a Mouse Model
Available to PurchaseSubject Area:
Gastroenterology
Elisabeth Lippert, Petra Ruemmele, Florian Obermeier, Stefan Goelder, Claudia Kunst, Gerhard Rogler, Nadja Dunger, Helmut Messmann, Arndt Hartmann, Esther Endlicher
Journal:
Digestion
Digestion (2017) 95 (4): 275–280.
Published Online: 12 May 2017
..., colon samples were analysed macroscopically and microscopically. Results: Mice receiving 10% anthocyanins showed significantly ( p < 0.004) less reduced colon length (12.1 cm [8.5-14.4 cm]) as compared to controls (11.2 cm [9.8-12.3]) indicating less inflammation. Mice fed with 10% anthocyanin-rich...
Journal Articles
Galectin-3 Modulates Experimental Colitis
Available to PurchaseSubject Area:
Gastroenterology
Elisabeth Lippert, Manuela Stieber-Gunckel, Nadja Dunger, Werner Falk, Florian Obermeier, Claudia Kunst
Journal:
Digestion
Digestion (2015) 92 (1): 45–53.
Published Online: 17 July 2015
... weight loss compared to that of controls. In acute and chronic colitis, gal-3 treatment resulted in a significant suppression of colonic IL-6. Conclusion: Gal-3 significantly reduces inflammation in acute and chronic DSS colitis in mice indicating a potential role in intestinal inflammation. Gal-3...
Journal Articles
Intestinal Endometriosis: Mimicker of Inflammatory Bowel Disease?
Available to PurchaseSubject Area:
Gastroenterology
Antonio Guadagno, Federica Grillo, Valerio Gaetano Vellone, Simone Ferrero, Alberto Fasoli, Roberto Fiocca, Luca Mastracci
Journal:
Digestion
Digestion (2015) 92 (1): 14–21.
Published Online: 04 June 2015
... alterations in the absence of significant inflammation. Three cases showed marked inflammatory and architectural mucosal changes making a differential diagnosis with IBD particularly challenging. On follow-up, however, these patients remained symptom-free and with no need for anti-inflammatory therapy after...
Journal Articles
Helicobacter pylori Infection and the Respiratory System: A Systematic Review of the Literature
Available to PurchaseSubject Area:
Gastroenterology
Journal:
Digestion
Digestion (2011) 84 (3): 212–220.
Published Online: 12 July 2011
... by chronic inflammation as well as increased immune response. Recent studies have evaluated the relation between various respiratory disorders and H. pylori infection. The aim of this systematic review was to scrutinize the relevant literature and the mechanisms that could underlie a role for H. pylori...
Journal Articles
Gene Expression following Exposure to Celecoxib in Humans: Pathways of Inflammation and Carcinogenesis Are Activated in Tumors but Not Normal Tissues
Available to PurchaseSubject Area:
Gastroenterology
Eyal Sagiv, Michal Sheffer, Diana Kazanov, Shiran Shapira, Inna Naumov, Sarah Kraus, Eytan Domany, Nadir Arber
Journal:
Digestion
Digestion (2011) 84 (3): 169–184.
Published Online: 05 May 2011
... before and after treatment, among which 310 genes did not show the same differential expression in the placebo group or normal samples. These genes were significantly related to pathways of cell cycle regulation and inflammation, and of note was the TGF-β pathway, which held a strong association...
Journal Articles
Interleukin-1Beta and Interleukin-8 Expression Correlate with the Histomorphological Changes in Esophageal Mucosa of Patients with Erosive and Non-Erosive Reflux Disease
Available to PurchaseSubject Area:
Gastroenterology
Klaus Mönkemüller, Thomas Wex, Doerthe Kuester, Lucia C. Fry, Ulrich Peitz, Mike Beyer, Albert Roessner, Peter Malfertheiner
Journal:
Digestion
Digestion (2009) 79 (3): 186–195.
Published Online: 03 April 2009
... reflux disease Interleukin, cytokines Inflammation Histology Gastroesophageal reflux disease (GERD) is one of the most prevalent gastrointestinal (GI) disorders in the world [ 1, 2 ]. The classic endoscopic characteristics of erosive reflux disease (ERD) are distal esophageal mucosal breaks...
Journal Articles
Effect of Experimental Colitis on Bone Metabolism in the Rat
Available to PurchaseSubject Area:
Gastroenterology
Journal:
Digestion
Digestion (1994) 55 (4): 229–233.
Published Online: 05 February 2009
... urinary hydroxyproline and osteopenia. Considering site of inflammation, diet, sex, and absence of therapy, inflammatory mediators, e.g. cytokines, with known catabolic effects on bone, might be involved in the pathogenesis of osteopenia. 25 06 1993 25 10 1993 1 07 1994 © 1994 S...
Journal Articles
Inflammation, Capillary Leakage and Healing of Experimental Gastric Ulcers in the Rat
Available to PurchaseSubject Area:
Gastroenterology
Journal:
Digestion
Digestion (1991) 50 (3-4): 170–175.
Published Online: 04 February 2009
...C.C. Schuerer-Maly; K. Ott; U. Emmenegger; F. Hoeflin; E.O. Müller; F. Halter Little information is available on the role of inflammation and small vessel alteration in the development and healing of peptic ulcers. We studied the spontaneous healing of experimental ulcers in the rat stomach...
Journal Articles
Novel Aspect of Crohn’s Disease: Increased Content of Platelet-Activating Factor in Ileal and Colonic Mucosa
Available to PurchaseSubject Area:
Gastroenterology
Journal:
Digestion
Digestion (1990) 46 (4): 199–204.
Published Online: 03 February 2009
... of colonic inflammation as judged macroscopically. These findings add further support to the importance of bioactive lipids in inflammatory bowel disease and suggest a possible role for PAF-acether in Crohn’s disease. 3 11 1989 1 07 1990 © 1990 S. Karger AG, Basel Copyright / Drug Dosage...
Journal Articles
Breast Cancer Resistance Protein and P-Glycoprotein Expression in Patients with Newly Diagnosed and Therapy-Refractory Ulcerative Colitis Compared with Healthy Controls
Available to PurchaseSubject Area:
Gastroenterology
Heike Gutmann, Petr Hruz, Christian Zimmermann, Alexander Straumann, Luigi Terracciano, Felix Hammann, Frank Lehmann, Christoph Beglinger, Juergen Drewe
Journal:
Digestion
Digestion (2008) 78 (2-3): 154–162.
Published Online: 03 December 2008
..., in colonic tissue sections with no visible signs of inflammation of 10 newly diagnosed UC patients and in 12 tissue sections obtained from acutely inflamed sections of newly diagnosed UC patients, in colonic tissue sections with no visible signs of inflammation of 11 therapy-refractory patients and in 12...
Journal Articles
Diminished Expression of Apical Sodium-Dependent Bile Acid Transporter in Gallstone Disease Is Independent of Ileal Inflammation
Available to PurchaseSubject Area:
Gastroenterology
Arthur Holzer, Simone Harsch, Olga Renner, André Strohmeyer, Silke Schimmel, Jan Wehkamp, Peter Fritz, Eduard F. Stange
Journal:
Digestion
Digestion (2008) 78 (1): 52–59.
Published Online: 02 October 2008
... a significant downregulation of this transporter. Aim: To test whether subclinical ileal inflammation contributes to gallstone disease. Methods: Biopsies from terminal ileum of female subjects with gallstone disease (n = 7), active Crohn’s disease (n = 17) and controls (n = 22) were investigated. mRNA...
Journal Articles
Gastric Perception Thresholds Are Low and Sensory Neuropeptide Levels High in Helicobacter pylori- Positive Functional Dyspepsia
Available to PurchaseSubject Area:
Gastroenterology
Hubert Mönnikes, Ivo R. van der Voort, Birgit Wollenberg, Ingeborg Heymann-Mönnikes, Johannes J. Tebbe, Wibke Alt, Rudolf Arnold, Burghard F. Klapp, Bertram Wiedenmann, Gerard P. McGregor
Journal:
Digestion
Digestion (2005) 71 (2): 111–123.
Published Online: 20 April 2005
... distension. Substance P (SP) and calcitonin gene-related peptide (CGRP) are involved in the sensitization of afferent neuronal pathways due to chronic inflammation. The role of Helicobacter pylori- induced gastric mucosal inflammation in the pathogenesis of FD is controversial. The aim of this study...
Journal Articles
Beneficial Effects of Batimastat (BB-94), a Matrix Metalloproteinase Inhibitor, in Rat Experimental Colitis
Available to PurchaseSubject Area:
Gastroenterology
Pierluigi Di Sebastiano, Fabio F. di Mola, Luciano Artese, Cosmo Rossi, Giuseppe Mascetta, Heinz Pernthaler, Paolo Innocenti
Journal:
Digestion
Digestion (2001) 63 (4): 234–239.
Published Online: 29 June 2001
...% saline served as controls. Animals were killed after seven days; segments of colon were removed and used for histological score of inflammation and myeloperoxidase (MPO) activity. Results: Rats receiving only intracolonic 0.9% saline showed no evidence of colitis. The inflammation score was 0.9, MPO...
Journal Articles
Potential Pitfalls in the Differential Diagnosis of Irritable Bowel Syndrome
Available to PurchaseSubject Area:
Gastroenterology
A. Smout, F. Azpiroz, G. Coremans, M. Dapoigny, S. Collins, S. Müller-Lissner, F. Pace, R. Stockbrügger, M. Vatn, P. Whorwell
Journal:
Digestion
Digestion (2000) 61 (4): 247–256.
Published Online: 16 June 2000
.... 2000 Inflammation Antibiotic-associated diarrhea Carbohydrate malabsorption Food allergy Food intolerance Bile salt malabsorption Hormone-induced diarrhea Colitis Intestinal pseudo-obstruction Hirschsprung’s disease. Many of the organic diseases that may mimic symptoms...
Journal Articles
Implications of Tachykinins and Calcitonin Gene-Related Peptide in Inflammatory Bowel Disease
Available to PurchaseSubject Area:
Gastroenterology
Journal:
Digestion
Digestion (1998) 59 (4): 269–283.
Published Online: 03 August 1998
... neurons contributes to motor, secretory, vascular and immunological disturbances in intestinal anaphylaxis, infection and inflammation. In a therapeutic perspective it seems conceivable that tachykinin and CGRP receptors antagonists can be employed as spasmolytic, antidiarrhoeal, anti-inflammatory...